General Pathology Practice Questions

Q: Corrugated collagenous rings surrounding lymphocytes and plasma cells in the walls of inflammatory cysts are called?

Hyaline bodies. ### Explanation **Correct Answer: B. Hyaline bodies (Rushton bodies)** In the context of oral pathology and inflammatory cysts (such as radicular cysts), **Hyaline bodies**, also known as **Rushton bodies**, are characteristic microscopic findings. They appear as eosinophilic, linear, curved, or "corrugated" glassy structures. They are typically found within the epithelial lining or the underlying connective tissue wall, often surrounded by chronic inflammatory cells like lymphocytes and plasma cells. While their exact origin is debated, they are generally considered to be a secretory product of odontogenic epithelium. **Analysis of Incorrect Options:** * **A. Ruston bodies:** This is a common distractor. The correct eponym is **Rushton bodies** (with an 'h'). While phonetically similar, "Ruston" is technically incorrect in a formal examination context. * **C. Howell-Jolly bodies:** These are small, round, purple-staining nuclear remnants (DNA) found inside **red blood cells**. They are typically seen in patients with splenic atrophy or post-splenectomy. * **D. Pappenheimer bodies:** These are abnormal granules of **iron** (ferritin aggregates) found inside red blood cells, visualized with Wright or Giemsa stains. They are characteristic of sideroblastic anemia. **High-Yield Clinical Pearls for NEET-PG:** * **Rushton Bodies:** Exclusively found in **odontogenic cysts** (most commonly Radicular and Dentigerous cysts). They are brittle and may show a "cracked" appearance. * **Civatte Bodies:** Found in Lichen Planus (apoptotic keratinocytes). * **Verocay Bodies:** Found in Schwannomas (Antoni A areas). * **Schaumann Bodies:** Laminated calcium/protein concretions found in Sarcoidosis.

Question 1

What is a characteristic feature of apoptosis?

Accepted Answer

Cell membrane intact

Answer

Cytoplasmic eosinophilia

Answer

Nuclear moulding

Answer

Cell swelling

Question 2

Corrugated collagenous rings surrounding lymphocytes and plasma cells in the walls of inflammatory cysts are called?

Accepted Answer

Hyaline bodies

Answer

Ruston bodies

Answer

Howell-Jolly bodies

Answer

Papenheimer bodies

Question 3

Which of the following is a vasoconstricting mediator?

Accepted Answer

Thromboxane-A2

Answer

Prostacyclin

Answer

PGD2

Answer

Lipoxins

Question 4

Which of the following conditions follows an autosomal dominant inheritance pattern?

Accepted Answer

Hereditary spherocytosis

Answer

Albinism

Answer

Sickle cell anemia

Answer

Thalassemia

Question 5

Which of the following pigment is deposited in aging heart?

Accepted Answer

Lipofuscin

Answer

Hemosiderin

Answer

Ceruloplasmin

Answer

None of the above

Question 6

Which one of the following is NOT a characteristic feature of an autosomal recessive disorder?

Accepted Answer

Wide variation in phenotype within a family

Answer

Males and females are equally affected

Answer

Parents of an affected child are usually heterozygous carriers

Answer

Display a horizontal pattern in pedigrees

Question 7

Metastatic calcification predominantly affects which of the following organs, except?

Accepted Answer

Pancreas

Answer

Lungs

Answer

Kidney

Answer

Media of arteries

Question 8

Which of the following is characteristic of Langerhans cells?

Accepted Answer

Birbeck's granules

Answer

Badminton racquet appearance

Answer

CD100a

Answer

MPO +

Question 9

Which of the following substances is NOT secreted by Eosinophils?

Accepted Answer

Hydrolytic enzyme

Answer

Major basic protein

Answer

Reactive form of oxygen

Answer

Eosinophilic chemotactic factor

Question 10

Multifactorial inheritance is most likely to play a role in which of the following conditions?

Accepted Answer

Cleft lip

Answer

Marfan's syndrome

Answer

Down's syndrome

Answer

Erythroblastosis fetalis

General Pathology — MCQs

General Pathology — MCQs

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