General Pathology Practice Questions

Q: A permanent tooth with a local hypoplastic deformity in a crown is called?

Turner's tooth. ### Explanation **Turner’s Tooth (Turner’s Hypoplasia)** The correct answer is **Turner’s tooth**. This condition refers to a permanent tooth that exhibits a localized enamel hypoplastic deformity. It most commonly occurs due to an **extension of periapical infection** from the overlying deciduous tooth or **local mechanical trauma** during the development of the permanent tooth bud. The inflammatory process or trauma disrupts the ameloblasts (enamel-forming cells), leading to defects ranging from white/brown discoloration to severe pitting and coronal deformity. It most frequently affects permanent premolars. **Analysis of Incorrect Options:** * **Taurodontism:** This is a morphologic variation where the tooth body is elongated and the roots are shortened, leading to an apical displacement of the furcation ("bull-like" teeth). It is a shape anomaly, not a localized enamel hypoplasia. * **Enameloma (Enamel Pearl):** This is a small, focal mass of ectopic enamel found typically on the root surface, especially near the bifurcation of molar teeth. * **Ghost Teeth (Regional Odontodysplasia):** This is a rare developmental anomaly affecting all dental tissues (enamel, dentin, and pulp) in a specific quadrant. On X-ray, these teeth appear thin and shell-like with very little mineralization, giving them a "ghostly" appearance. **High-Yield NEET-PG Pearls:** * **Most common site:** Permanent maxillary incisors (due to trauma) or permanent premolars (due to periapical infection of deciduous molars). * **Amelogenesis Imperfecta:** Unlike Turner’s tooth (which is localized/acquired), Amelogenesis Imperfecta is a genetic condition affecting the enamel of *all* teeth. * **Syphilitic Hypoplasia:** Congenital syphilis causes specific enamel defects known as **Hutchinson’s incisors** (notched) and **Mulberry molars** (globular occlusal surfaces).

Question 1

What is the benign neoplasm of brown fat noted in the oral/pharyngeal region?

Accepted Answer

Hibernoma

Answer

Lipoma

Answer

Teratoma

Answer

Brown tumor

Question 2

What is the typical number of chromosomes in an individual with Klinefelter syndrome?

Accepted Answer

47

Answer

46

Answer

45

Answer

44

Question 3

Which of the following is false regarding cystic fibrosis?

Accepted Answer

Associated with chromosome 7p

Answer

Associated with the CFTR gene

Answer

Autosomal recessive inheritance

Answer

Recurrent respiratory tract infection

Question 4

A permanent tooth with a local hypoplastic deformity in a crown is called?

Accepted Answer

Turner's tooth

Answer

Taurodontism

Answer

Enameloma

Answer

Ghost teeth

Question 5

Which of the following is NOT a mononuclear-macrophage?

Accepted Answer

B-cells

Answer

Histiocytes

Answer

Microglia

Answer

Kupffer cells

Question 6

Edward syndrome is characterized by which of the following chromosomal abnormalities?

Accepted Answer

Trisomy 18

Answer

Trisomy 13

Answer

Trisomy 21

Answer

Trisomy 20

Question 7

Cytosolic cytochrome C plays an important function in?

Accepted Answer

Apoptosis

Answer

Cell necrosis

Answer

Electron transport chain

Answer

Cell division

Question 8

Which of the following is the hallmark of programmed cell death?

Accepted Answer

Apoptosis

Answer

Coagulation necrosis

Answer

Fibrinoid necrosis

Answer

Liquefaction necrosis

Question 9

Natural killer (NK) cells attack which of the following types of cells?

Accepted Answer

Cells which are unable to express MHC class I

Answer

Cells which express MHC class I

Answer

MHC cells which express MHC class II

Question 10

Psammoma bodies show which type of calcification?

Accepted Answer

Dystrophic

Answer

Metastatic

Answer

Secondary

Answer

Any of the above

General Pathology — MCQs

General Pathology — MCQs

On this page

Practice by Chapter

Want unlimited practice?