General Pathology Practice Questions

Q: Which of the following is a true neoplasm of functional cementoblasts?

Benign cementoblastoma. **Explanation:** The correct answer is **Benign Cementoblastoma**. This condition is classified as the only **true neoplasm** of cementoblasts. It is a rare, odontogenic tumor characterized by the proliferation of functional cementoblasts that form a mass of cementum-like tissue attached directly to the root of a tooth. **Why the other options are incorrect:** * **Periapical Cemental Dysplasia (PCD):** This is a **reactive/dysplastic** process, not a neoplasm. It typically occurs at the apex of vital mandibular anterior teeth and progresses through osteolytic, cementoblastic, and mature stages. * **Familial Cemental Dysplasia:** Also known as Gigantiform Cementoma, this is a hereditary **dysplastic** condition involving multiple quadrants of the jaws. While aggressive, it is considered a developmental/dysplastic anomaly rather than a true neoplasm. * **Hypercementosis:** This is a **non-neoplastic** deposition of excessive cementum on the roots of teeth. It is often associated with local factors (inflammation, trauma) or systemic conditions like Paget’s disease of bone. **High-Yield Clinical Pearls for NEET-PG:** * **Radiographic Hallmark:** Benign cementoblastoma appears as a well-defined **radiopaque mass** attached to the tooth root (usually the mandibular first molar), surrounded by a characteristic **radiolucent halo**. * **Clinical Feature:** Unlike many other odontogenic tumors, it is often associated with **localized pain and swelling**. * **Key Association:** The involved tooth remains **vital**, but the tumor is physically attached to the root, often requiring extraction of the tooth along with the lesion.

Question 1

In which mode of inheritance are males more commonly affected than females?

Accepted Answer

X-linked dominant

Answer

Autosomal dominant

Answer

Autosomal recessive

Answer

None of these

Question 2

Hypertrophy is a result of what process?

Accepted Answer

Increased production of cellular proteins

Answer

Growth factor-driven proliferation of mature cells

Answer

Reprogramming of stem cells

Answer

Decreased protein synthesis and increased protein degradation in cells

Question 3

What is the color of hemosiderin?

Accepted Answer

Brown

Answer

Black

Answer

Blue

Answer

Yellow

Question 4

All of the following is an example of squamous metaplasia except:

Accepted Answer

Esophagus in gastric reflux

Answer

Cervix in case of chronic irritation

Answer

Respiratory tract in case of smoking

Answer

Stone in bile ducts

Question 5

The retinoblastoma gene is located on which chromosome?

Accepted Answer

Chromosome 13

Answer

Chromosome 6

Answer

Chromosome 9

Answer

Chromosome 21

Question 6

Severe generalized edema is called as:

Accepted Answer

Anasarca.

Answer

Pitting edema.

Answer

Myxoedema

Answer

Dependent edema

Question 7

Necrosis with putrefaction is called as:

Accepted Answer

Gangrene

Answer

Desiccation

Answer

Liquefaction

Answer

Coagulative necrosis

Question 8

Which of the following is a true neoplasm of functional cementoblasts?

Accepted Answer

Benign cementoblastoma

Answer

Periapical cemental dysplasia

Answer

Familial cemental dysplasia

Answer

Hypercementosis

Question 9

When does the tensile strength of a wound start to increase?

Accepted Answer

7 to 10 days

Answer

Immediate suture of the wound

Answer

3 to 4 days

Answer

6 months

Question 10

On electron microscopy, amyloid characteristically exhibits which of the following?

Accepted Answer

7.5-10 nm fibrils

Answer

Beta-pleated sheets

Answer

Hyaline globules

Answer

20-25 nm fibrils

General Pathology — MCQs

General Pathology — MCQs

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