Gastrointestinal Pathology Practice Questions

Question 1

Which of the following is FALSE regarding autoimmune atrophic gastritis?

Accepted Answer

Hyperchlorhydria

Answer

Loss of parietal cells

Answer

Hyperplasia of G cells

Answer

Hypertrophy of enterochromaffin cells

Question 2

Duke's stage C2 refers to carcinoma:

Accepted Answer

Rectum with metastasis to inferior mesenteric lymph nodes

Answer

Bladder penetrating the extravesical fat

Answer

Bladder with metastasis to internal iliac lymph nodes

Answer

With histological features of 75% anaplastic cells

Question 3

Which type of carcinoid is associated with the greatest incidence of metastasis?

Accepted Answer

Pancreatic carcinoid

Answer

Appendix carcinoid

Answer

Colonic carcinoid

Answer

Hepatic carcinoid

Question 4

Which of the following is NOT considered a premalignant condition?

Accepted Answer

Hyperplastic polyp

Answer

Tubulovillous adenoma

Answer

Familial adenomatosis

Answer

Villous adenoma

Question 5

A peptic ulcer is associated with all of the following conditions except one?

Accepted Answer

Pernicious anemia

Answer

Cirrhosis

Answer

Zollinger-Ellison syndrome

Answer

Primary hyperparathyroidism

Question 6

What is the commonest site involved in ileocecal tuberculosis?

Accepted Answer

Intestinal mucosa

Answer

Intestinal wall

Answer

Lymph node

Answer

Mesentery

Question 7

A patient with intestinal malabsorption shows marked improvement when flour products are removed from the diet. At the height of the disease, what histologic changes would be seen at which of the following sites?

Accepted Answer

Proximal small bowel

Answer

Distal large bowel

Answer

Distal small bowel

Answer

Entire large bowel

Question 8

Which of the following statements is NOT true about Gastrointestinal Stromal Tumors (GIST)?

Accepted Answer

They have a high propensity for malignant change.

Answer

The stomach is the most common site.

Answer

They are associated with c-KIT mutations.

Answer

Histology typically shows spindle-shaped cells.

Question 9

Linitis plastica is seen in which of the following conditions?

Accepted Answer

Carcinoma of the stomach

Answer

Carcinoma of the liver

Answer

Carcinoma of the lung

Answer

Carcinoma of the esophagus

Question 10

Which of the following is NOT a pathologic feature of H. pylori chronic gastritis?

Accepted Answer

Eosinophilic infiltrates

Answer

Intraepithelial neutrophil deposits

Answer

Affects intestinal gland formation in the stomach

Answer

Subepithelial plasma cell deposits

Gastrointestinal Pathology — MCQs

Gastrointestinal Pathology — MCQs

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