Endocrine Pathology — MCQs

A 74-year-old woman is admitted to the hospital in an obtunded condition. Her temperature is 37°C, pulse is 95/min, respirations are 22/min, and blood pressure is 90/60 mm Hg. She appears dehydrated and has poor skin turgor. Her serum glucose level is 872 mg/dL. Urinalysis shows 4+ glucosuria, but no ketones, protein, or blood. Which of the following factors is most important in the pathogenesis of this patient's condition?

Which thyroid condition cannot be diagnosed by FNAC?

A 42-year-old woman presents with a 7-month history of increasing fullness in her neck. Physical examination reveals a diffusely and asymmetrically enlarged, nodular thyroid gland with no lymphadenopathy. Thyroidectomy is performed. Gross examination shows a multicentric thyroid neoplasm. Microscopically, the neoplasm is composed of polygonal-to spindle-shaped cells forming nests and trabeculae, with a prominent, pink hyaline stroma that stains positively with Congo red. Electron microscopy reveals intracytoplasmic, membrane-bound, electron-dense granules. Immunohistochemical staining for which of the following antigens is most useful for the diagnosis of this neoplasm?

All of the following are true regarding thyroid adenoma, except?

Increased urine levels of 5-HIAA are associated with which condition?

Which of the following represents a true increase in islet cells?

Zellballen pattern is seen in which of the following conditions?

Which of the following is a tumor marker for medullary thyroid carcinoma?

A surgeon operates on a patient with a pheochromocytoma involving the adrenal gland and requests intraoperative frozen sections. Which of the following criteria can be used to determine if the lesion is benign or malignant?

What is a diagnostic feature of parathyroid carcinoma?