Gynecological Disorders Practice Questions

Q: What is used to aid identification of areas of dysplasia in colposcopy?

3 - 5% acetic acid. ***3 - 5% acetic acid*** - **Acetic acid** dehydrates cells and causes nuclear proteins and keratins to coagulate, making areas with high nuclear-to-cytoplasmic ratio (like dysplastic cells) appear **acetowhite**. - This transient **acetowhite change** helps colposcopists identify dysplastic lesions that are not visible to the naked eye. *Acetocarmine red* - This is a stain used in **cytogenetics** for staining chromosomes, not for colposcopic identification of dysplasia. - It highlights nuclear material and is not applied topically during a colposcopic examination to reveal acetowhite changes. *1 % formic acid* - **Formic acid** is a strong organic acid used in various industrial applications and as a decalcifying agent in histology. - It is not used as a diagnostic agent in colposcopy to identify dysplastic areas. *1 % alcohol* - **Alcohol** is an antiseptic and dehydrating agent, but it does not selectively identify dysplastic cells through an acetowhite change like acetic acid. - It is not routinely used in colposcopy for the purpose of highlighting abnormal epithelial areas.

Q: Which of the following is a risk factor for ectopic pregnancy?

All of the options. ***All of the options*** - **Intrauterine contraceptive devices (IUCDs)**, a history of **infertility**, and **tubal endometriosis** are all recognized risk factors for ectopic pregnancy. - These factors either interfere with normal tubal function and ovum transport or create an environment conducive to implantation outside the uterus. *IUCD* - While IUCDs are highly effective at preventing intrauterine pregnancies, they do not prevent ectopic pregnancies with the same efficacy, thus slightly *increasing the relative risk* of an ectopic pregnancy if a pregnancy does occur. - The presence of an IUCD can also induce a mild inflammatory reaction in the fallopian tubes, potentially impairing normal ciliary function and ovum transport. *History of infertility* - Many causes of infertility, such as **pelvic inflammatory disease (PID)**, **endometriosis**, or previous **tubal surgery**, can damage the fallopian tubes and impair their ability to transport a fertilized egg to the uterus. - Infertility treatments, particularly those involving **assisted reproductive technologies (ART)**, can also increase the risk of ectopic pregnancy due to manipulation of gametes and embryos. *Tubal endometriosis* - **Endometriotic implants** within the fallopian tubes can cause structural damage, inflammation, scarring, and alterations in the tubal motility. - These changes can obstruct or slow the passage of a fertilized egg, leading to its implantation within the tube rather than the uterus.

Q: What is the most common germ cell tumor of the ovary?

Mature cystic teratoma. ***Mature cystic teratoma*** - **Mature cystic teratomas**, also known as **dermoid cysts**, are the most common type of **ovarian germ cell tumor**, accounting for approximately 10-20% of all ovarian neoplasms. - They are typically benign and characterized by the presence of **tissue from all three germ layers** (ectoderm, mesoderm, endoderm), often including hair, teeth, bone, and sebaceous material. *Dysgerminoma* - **Dysgerminomas** are the most common **malignant** germ cell tumor of the ovary, but overall less common than mature cystic teratomas. - They are analogous to **seminomas** in males and are often associated with high levels of **lactate dehydrogenase (LDH)**. *Serous cystadenoma* - **Serous cystadenomas** are the most common type of **epithelial ovarian tumor**, not germ cell tumors, and are typically benign. - They originate from the surface epithelium of the ovary and are filled with clear, watery fluid. *Yolk sac tumor* - **Yolk sac tumors** (endodermal sinus tumors) are rare, highly malignant germ cell tumors of the ovary. - They are characterized by elevated levels of **alpha-fetoprotein (AFP)** and the presence of **Schiller-Duval bodies**.

Q: What is the condition characterized by the ingrowth of both glandular and stromal components of the endometrium into the myometrium?

Adenomyosis. ***Adenomyosis*** - **Adenomyosis** is defined by the presence of **endometrial glands and stroma within the myometrium**. - This ectopic tissue causes the uterus to become enlarged and boggy, often leading to **dysmenorrhea** and **menorrhagia**. *Courvelaire uterus* - **Couvelaire uterus** is a condition where there is **hemorrhage into the myometrium** as a result of **placental abruption**. - It is an acute obstetric complication, not a chronic ingrowth of endometrial tissue. *Placenta accreta* - **Placenta accreta** involves abnormal adherence of the **placenta to the myometrium**, with villi invading the uterine wall. - While it involves invasion into the myometrium, it is specific to the placenta and occurs during pregnancy, not involving endometrial glands and stroma themselves. *Uterine fibroid* - A **uterine fibroid** (leiomyoma) is a **benign tumor of smooth muscle** within the myometrium. - It is composed primarily of muscle and fibrous connective tissue, not endometrial glandular tissue.

Q: Meigs syndrome is associated with which tumor ?

Fibroma. ***Fibroma*** - **Meigs syndrome** is defined by the classic triad of a **benign ovarian fibroma** (or fibroma-like tumor such as thecoma), **ascites**, and **pleural effusion**. - The effusions **resolve completely after tumor removal**, which is a key diagnostic feature. - While other ovarian tumors can cause ascites and pleural effusion, the specific combination with a **fibroma** is characteristic of true Meigs syndrome. *Cystadenoma* - **Cystadenomas** (serous or mucinous) are common benign ovarian tumors that are typically cystic. - They can cause ascites and pleural effusion, a condition termed **"pseudo-Meigs syndrome"**, but they lack the fibrous solid component central to the definition of true Meigs syndrome. - The distinction is important for classification purposes, though clinical management may be similar. *Dysgerminoma* - A **dysgerminoma** is a malignant germ cell tumor of the ovary, most common in young women. - While it can cause ascites as a feature of malignancy or peritoneal spread, it is not a benign tumor and is therefore not associated with Meigs syndrome. - Malignant tumors causing effusions do not fit the criteria for Meigs syndrome. *Teratoma* - **Teratomas** are germ cell tumors that can be benign (mature cystic teratoma or dermoid cyst) or malignant (immature teratoma). - Though they can rarely cause ascites and pleural effusion (pseudo-Meigs syndrome), especially if complicated by rupture, torsion, or malignant transformation, they are not fibromas and thus do not fit the criteria for true Meigs syndrome. - The most common complication of dermoid cysts is torsion, not Meigs syndrome.

Q: What is the most common type of fibroid?

Intramural. ***Intramural*** - **Intramural fibroids** are located within the **uterine wall muscle (myometrium)** and are the most prevalent type. - Their presence often leads to **enlargement of the uterus** and can cause symptoms like **heavy menstrual bleeding** and **pelvic pressure**. *Subserosal* - **Subserosal fibroids** grow on the **outer surface of the uterus** and may project outwards. - While common, they are found **less frequently** than intramural fibroids and often cause **pressure symptoms** more than bleeding issues. *Cervical* - **Cervical fibroids** are located in the **cervix**, the lower part of the uterus, and are relatively rare. - They can cause symptoms such as **dyspareunia**, **urinary obstruction**, or **bleeding** due to their position. *Submucosal* - **Submucosal fibroids** are located just beneath the **endometrial lining** of the uterus, protruding into the uterine cavity. - Although they are the **least common type**, they are associated with the **most severe symptoms**, including heavy and prolonged menstrual bleeding and infertility.

Q: What type of tubal damage is associated with Pelvic Inflammatory Disease (PID) caused by Neisseria gonorrhoeae?

Endotubal. ***Endotubal*** - *Neisseria gonorrhoeae* infection in **Pelvic Inflammatory Disease (PID)** primarily affects the **mucosa lining the fallopian tubes**, causing inflammation and damage from within. - This **endotubal inflammation** can lead to scarring, adhesion formation, and destruction of the ciliary epithelium, impairing tubal function. *Peritubal* - **Peritubal damage** refers to inflammation and adhesions on the **exterior surface of the fallopian tubes**, often involving surrounding structures. - While PID can eventually cause peritubal adhesions, the **primary and initial site of damage** from *N. gonorrhoeae* is endotubal. *Extratubal* - **Extratubal** damage implies pathology located **completely outside** the fallopian tube itself, such as in the ovaries or peritoneum. - Although PID is a broad infection of the upper genital tract, the **direct damage** to the tube from *N. gonorrhoeae* starts inside the lumen. *Juxtatubal* - **Juxtatubal** refers to damage located **adjacent to** or in close proximity to the fallopian tube, but not necessarily within it or on its surface. - This term is less specific regarding the primary site of infection and damage caused by *N. gonorrhoeae* in the fallopian tubes.

Q: Most common ovarian cyst to undergo torsion?

Benign cystic teratoma. ***Benign cystic teratoma*** - These cysts are the **most common ovarian tumors** and have a higher likelihood of undergoing torsion due to their typical size and irregular shape, making them prone to twisting on their pedicle. - Their often **heterogeneous consistency** (containing various tissues like fat, hair, and bone) can also contribute to uneven weight distribution, increasing the risk of torsion. *Dysgerminoma* - While it is a germ cell tumor, **dysgerminomas are malignant** and generally less likely to undergo torsion than benign cystic teratomas. - They tend to grow rapidly and are often solid, reducing the chance of twisting compared to more mobile, pediculated cysts. *Ovarian fibroma* - **Ovarian fibromas are solid, benign tumors** that are typically less mobile due to their density and attachment, making torsion less common. - While they can be associated with Meigs syndrome, their risk of torsion is lower than that of cystic lesions. *Brenner's tumor* - **Brenner's tumors are uncommon, solid epithelial tumors** of the ovary and are rarely associated with ovarian torsion. - Their solid nature and typically small to moderate size make them less prone to twisting on their vascular pedicle.

Q: In cases of genital tuberculosis, which condition is most commonly associated with tubal adhesions, fibrosis, and hydrosalpinx formation?

Tuberculosis of the fallopian tube. ***Tuberculosis of the fallopian tube*** - **Tubal tuberculosis** is the **most common site** of genital tuberculosis (90-95% of cases), directly affecting the fallopian tubes - Leads to severe inflammatory responses causing **adhesions**, **fibrosis**, and ultimately **hydrosalpinx formation** - This is a **significant cause of infertility** due to tubal obstruction and distortion - Classic presentation includes bilateral involvement with **beaded appearance** of tubes *Tuberculosis of the endometrium* - While **endometrial tuberculosis** is the second most common site (50-80% of cases), it's less directly associated with the specific tubal pathologies like **hydrosalpinx** - Endometrial involvement primarily leads to **menstrual irregularities**, **thin endometrium**, and **implantation failure**, rather than the structural distortion of the fallopian tubes - Often occurs secondary to tubal infection *Tuberculosis of the ovary* - **Ovarian tuberculosis** is less common (10-30% of cases) and typically presents as **tuberculous oophoritis** or ovarian mass - Does not directly cause the characteristic **hydrosalpinx** and extensive **tubal adhesions** seen with fallopian tube infection - Usually occurs in association with tubal disease *Tuberculosis of the cervix* - **Cervical tuberculosis** is rare (1-5% of cases) and presents as hypertrophic or ulcerative lesions - Does not cause **tubal adhesions**, **fibrosis**, or **hydrosalpinx formation** - Clinically may mimic cervical carcinoma

Q: What is the treatment of choice for a Bartholin cyst?

Marsupialization. ***Marsupialization*** - **Marsupialization** is the gold standard for Bartholin cysts because it creates a permanent opening for drainage, preventing recurrence. - This procedure involves incising the cyst, draining its contents, and then suturing the cyst walls to the surrounding skin, forming a **self-draining pouch**. *Aspiration* - **Aspiration** is generally not recommended as a primary treatment because it offers only temporary relief and has a high rate of recurrence. - The cyst will likely refill without a permanent drainage pathway, making it an ineffective long-term solution. *Observe* - **Observation** is only appropriate for very small, asymptomatic cysts that do not cause any discomfort or pain. - For symptomatic cysts, intervention is necessary to alleviate symptoms and prevent complications like infection. *Curettage and closure* - **Curettage and closure** is not a standard treatment for Bartholin cysts and would likely lead to immediate recurrence. - Simply excising the cyst without creating a new drainage duct for the Bartholin gland would result in the gland's continued blockage and cyst formation.

Question 1

What is used to aid identification of areas of dysplasia in colposcopy?

Accepted Answer

3 - 5% acetic acid

Answer

Acetocarmine red

Answer

1 % formic acid

Answer

1 % alcohol

Question 2

Which of the following is a risk factor for ectopic pregnancy?

Accepted Answer

All of the options

Answer

History of infertility

Answer

IUCD

Answer

Tubal endometriosis

Question 3

What is the most common germ cell tumor of the ovary?

Accepted Answer

Mature cystic teratoma

Answer

Dysgerminoma

Answer

Serous cystadenoma

Answer

Yolk sac tumor

Question 4

What is the condition characterized by the ingrowth of both glandular and stromal components of the endometrium into the myometrium?

Accepted Answer

Adenomyosis

Answer

Courvelaire uterus

Answer

Placenta accreta

Answer

Uterine fibroid

Question 5

Meigs syndrome is associated with which tumor ?

Accepted Answer

Fibroma

Answer

Cystadenoma

Answer

Dysgerminoma

Answer

Teratoma

Question 6

What is the most common type of fibroid?

Accepted Answer

Intramural

Answer

Subserosal

Answer

Cervical

Answer

Submucosal

Question 7

What type of tubal damage is associated with Pelvic Inflammatory Disease (PID) caused by Neisseria gonorrhoeae?

Accepted Answer

Endotubal

Answer

Peritubal

Answer

Extratubal

Answer

Juxtatubal

Question 8

Most common ovarian cyst to undergo torsion?

Accepted Answer

Benign cystic teratoma

Answer

Dysgerminoma

Answer

Ovarian fibroma

Answer

Brenner's tumor

Question 9

In cases of genital tuberculosis, which condition is most commonly associated with tubal adhesions, fibrosis, and hydrosalpinx formation?

Accepted Answer

Tuberculosis of the fallopian tube

Answer

Tuberculosis of the endometrium

Answer

Tuberculosis of the ovary

Answer

Tuberculosis of the cervix

Question 10

What is the treatment of choice for a Bartholin cyst?

Accepted Answer

Marsupialization

Answer

Aspiration

Answer

Observe

Answer

Curettage and closure

Gynecological Disorders — MCQs

Gynecological Disorders — MCQs

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