Vocal Cord Paralysis — MCQs
A patient presents with hoarseness and laryngoscopy reveals a warty, cauliflower-like growth on the vocal cord. Identify the most likely lesion.
A man takes peanut and develops tongue swelling, neck swelling, stridor, hoarseness of voice. What is the probable diagnosis?
Following total thyroidectomy, the patient develops respiratory stridor. The cause is:
Which of the following conditions is least likely to cause bilateral recurrent laryngeal nerve palsy?
A high tracheostomy may be indicated in:
During thyroidectomy, damage to which nerve leads to loss of high-pitched voice?
Most common nerve injured in ligation of inferior thyroid artery
A 50-year-old smoker presents with hoarseness, dysphagia, and weight loss. Flexible laryngoscopy shows a mass on the vocal cords. What is the next best step?
A 45-year-old patient presents with persistent hoarseness for 3 months. Which finding on indirect laryngoscopy is most concerning for malignancy?
Emergency tracheostomy is not indicated in
Vocal Cord Paralysis Indian Medical PG Practice Questions and MCQs
Question 1: A patient presents with hoarseness and laryngoscopy reveals a warty, cauliflower-like growth on the vocal cord. Identify the most likely lesion.
- A. Laryngeal papilloma (Correct Answer)
- B. Laryngeal malignancy
- C. Tracheomalacia
- D. Reinke’s edema
Explanation: ***Laryngeal papilloma*** - **Hoarseness** and a **warty, cauliflower-like growth** on the vocal cord are classic descriptions of a laryngeal papilloma, often caused by **HPV infection**. - These lesions can be solitary or multiple, and while benign, they can recur and cause voice changes and respiratory obstruction. *Laryngeal malignancy* - While hoarseness is a common symptom of laryngeal malignancy, the description of a **"warty, cauliflower-like growth"** is more characteristic of a papilloma than most typical carcinomas, which might appear more ulcerative or infiltrative. - Malignancies are more commonly associated with risk factors like **smoking and alcohol use**, and often present with other symptoms like dysphagia or weight loss. *Tracheomalacia* - **Tracheomalacia** refers to softening of the tracheal cartilage, leading to airway collapse, typically causing stridor or respiratory distress. - It does not present as a **discrete growth** on the vocal cords but rather as a diffuse structural weakness of the trachea. *Reinke’s edema* - **Reinke's edema** (polypoid corditis) is characterized by a **gelatinous or fluid-filled swelling** of the vocal cords, usually associated with chronic irritation like smoking. - It presents as a swollen, boggy appearance of the vocal cords, not a warty or cauliflower-like growth.
Question 2: A man takes peanut and develops tongue swelling, neck swelling, stridor, hoarseness of voice. What is the probable diagnosis?
- A. FB in larynx
- B. Angioneurotic edema (Correct Answer)
- C. Parapharyngeal abscess
- D. FB bronchus
Explanation: Andioneurotic edema - The combination of **tongue swelling**, **neck swelling**, **stridor**, and **hoarseness of voice** following peanut ingestion is highly suggestive of **angioneurotic edema**, a severe allergic reaction that can lead to airway obstruction [1]. - This is a life-threatening condition requiring immediate medical intervention, often associated with generalized **anaphylaxis** when triggered by allergens [2]. *FB in larynx* - While a **foreign body (FB) in the larynx** can cause stridor and hoarseness, the widespread swelling of the tongue and neck points away from a localized laryngeal obstruction [3]. - A laryngeal FB would typically be associated with a more sudden onset of choking and coughing, not diffuse edema [3]. *Parapharyngeal abscess* - A **parapharyngeal abscess** would typically present with **fever**, **severe throat pain**, and **trismus** (difficulty opening the mouth), which are not mentioned in this scenario. - The acute, rapid onset of symptoms after peanut consumption is inconsistent with the slower progression of an abscess. *FB bronchus* - A **foreign body in the bronchus** would primarily cause **coughing**, **wheezing**, and possibly **respiratory distress**, often unilateral, rather than severe global swelling of the tongue and neck. - Inspiratory stridor and hoarseness are more indicative of upper airway involvement than bronchial obstruction.
Question 3: Following total thyroidectomy, the patient develops respiratory stridor. The cause is:
- A. Unilateral recurrent laryngeal nerve paralysis
- B. Unilateral phrenic nerve paralysis
- C. Bilateral phrenic nerve paralysis
- D. Bilateral recurrent laryngeal nerve paralysis (Correct Answer)
Explanation: ***Bilateral recurrent laryngeal nerve paralysis*** - **Bilateral recurrent laryngeal nerve paralysis** is a serious complication of total thyroidectomy, leading to **adductor paralysis** of both vocal cords. - This results in a narrowed airway, causing inspiratory **stridor**, **dyspnea**, and potentially acute respiratory obstruction requiring reintubation or tracheostomy. *Unilateral recurrent laryngeal nerve paralysis* - **Unilateral recurrent laryngeal nerve paralysis** typically causes **hoarseness** due to the inability of one vocal cord to adduct properly. - It does not usually cause **stridor** or significant respiratory distress because the other vocal cord can still compensate for airway patency. *Unilateral phrenic nerve paralysis* - **Unilateral phrenic nerve paralysis** affects one side of the **diaphragm**, causing **dyspnea** and reduced lung capacity, particularly during exertion. - It does not directly cause **stridor**, which is a sound produced by turbulent airflow through a narrowed upper airway. *Bilateral phrenic nerve paralysis* - **Bilateral phrenic nerve paralysis** causes severe **respiratory failure** due to complete paralysis of the **diaphragm**, requiring mechanical ventilation. - While life-threatening, it does not directly manifest as **stridor**, as the primary issue is the inability to move air in and out through the lower respiratory system, not an obstruction in the upper airway.
Question 4: Which of the following conditions is least likely to cause bilateral recurrent laryngeal nerve palsy?
- A. Thyroid carcinoma
- B. Lymphadenopathy
- C. Thyroid surgery
- D. Aortic aneurysm (Correct Answer)
Explanation: ***Aortic aneurysm*** - An aortic aneurysm, especially of the ascending aorta, is **less likely to cause bilateral recurrent laryngeal nerve palsy** because the left recurrent laryngeal nerve typically hooks under the aortic arch, while the right nerve hooks under the subclavian artery. - For **bilateral involvement**, two separate and simultaneous lesions affecting both nerves would be required at different anatomical locations with this etiology, making it a rare cause. *Thyroid carcinoma* - An aggressive **thyroid carcinoma** can directly invade or compress the recurrent laryngeal nerves (RLNs) due to their proximity to the thyroid gland. - If the carcinoma is extensive or multifocal, it can lead to **bilateral involvement** by affecting both nerves. *Lymphadenopathy* - Significant **cervical or mediastinal lymphadenopathy** (e.g., due to metastatic disease or lymphoma) can compress or encase both recurrent laryngeal nerves. - This proximity allows for potential **bilateral compression or damage** to the nerves as they ascend in the tracheoesophageal grooves. *Thyroid surgery* - **Thyroidectomy** is a common cause of recurrent laryngeal nerve injury due to the nerves' close anatomical relationship with the thyroid gland. - **Bilateral recurrent laryngeal nerve palsy** can occur if both nerves are damaged during dissection, often due to surgical misidentification, thermal injury, or traction.
Question 5: A high tracheostomy may be indicated in:
- A. Advanced carcinoma of the larynx
- B. Severe bilateral vocal cord paralysis (Correct Answer)
- C. Chronic scleroma involving the larynx
- D. Recurrent respiratory papillomatosis (multiple papillomatosis of the larynx)
Explanation: ***Severe bilateral vocal cord paralysis*** - **High tracheostomy** may be indicated in severe bilateral vocal cord paralysis, particularly when both cords are paralyzed in the **median (adducted) position**, causing critical airway obstruction. - A high tracheostomy is performed at the level of the **2nd or 3rd tracheal ring**, closer to the site of obstruction at the glottic level, providing immediate airway access. - This can serve as temporary relief while definitive treatments like **arytenoidectomy, cordectomy, or vocal cord lateralization** are planned. - In emergency situations, high tracheostomy or cricothyroidotomy may be life-saving. *Advanced carcinoma of the larynx* - High tracheostomy is **contraindicated** in laryngeal carcinoma as it may: - Transect through tumor tissue - Cause tumor seeding in the tracheal stoma - Compromise subsequent **total laryngectomy** procedures - **Low tracheostomy** (below the tumor, at 4th-5th tracheal ring) is the standard approach to secure the airway while avoiding tumor interference. *Chronic scleroma involving the larynx* - Scleroma typically causes **subglottic stenosis** and involves extensive tracheal disease. - **Low tracheostomy** is preferred to bypass the diseased area completely. - A high tracheostomy would be too close to the pathological process, risking inadequate airway and complications. *Recurrent respiratory papillomatosis (multiple papillomatosis of the larynx)* - Tracheostomy is generally **avoided** in RRP due to the significant risk of **seeding papillomas** into the tracheal stoma and lower airways. - Management focuses on **repeated endoscopic laser ablation** or surgical excision to preserve laryngeal function. - If tracheostomy is absolutely necessary, meticulous technique and close follow-up are required.
Question 6: During thyroidectomy, damage to which nerve leads to loss of high-pitched voice?
- A. External branch of the superior laryngeal nerve (Correct Answer)
- B. Hypoglossal nerve
- C. Vagus nerve
- D. Recurrent laryngeal nerve
Explanation: ***External branch of the superior laryngeal nerve*** - The **external branch of the superior laryngeal nerve** innervates the **cricothyroid muscle**, which is responsible for tensing the vocal cords. - Damage to this nerve paralyzes the cricothyroid muscle, leading to an inability to tense the vocal cords, resulting in a **monotonous voice** and **loss of high-pitched tones**. *Hypoglossal nerve* - The **hypoglossal nerve (CN XII)** controls the muscles of the **tongue**, affecting articulation and swallowing, but not vocal pitch directly. - Damage primarily causes **tongue deviation** and **difficulty with speech (dysarthria)** and swallowing. *Vagus nerve* - The **vagus nerve (CN X)** gives rise to both the **superior laryngeal nerve** and the **recurrent laryngeal nerve**. - While damage to the vagus nerve trunk would affect vocalization, the question specifically asks about loss of high-pitched voice, which points to a more localized injury to one of its branches. *Recurrent laryngeal nerve* - The **recurrent laryngeal nerve** innervates most of the intrinsic laryngeal muscles, including the **thyroarytenoid** and **posterior cricoarytenoid muscles**, primarily affecting vocal cord adduction and abduction. - Damage typically causes **hoarseness** due to vocal cord paralysis, and in severe cases, difficulty breathing, but it does not specifically lead to the *loss of high-pitched voice* as directly as superior laryngeal nerve damage.
Question 7: Most common nerve injured in ligation of inferior thyroid artery
- A. Sympathetic trunk
- B. Phrenic nerve
- C. Recurrent laryngeal nerve (Correct Answer)
- D. External branch of superior laryngeal nerve
Explanation: **Recurrent laryngeal nerve** - The **recurrent laryngeal nerve (RLN)** runs in close proximity to the inferior thyroid artery, especially on the right side, making it highly vulnerable during ligation or thyroid surgery. - Injury to the RLN can cause **hoarseness** due to paralysis of the vocal cords, as it innervates most intrinsic laryngeal muscles. *Sympathetic trunk* - The **sympathetic trunk** lies more medially and posteriorly in the neck, generally not in the immediate surgical field for inferior thyroid artery ligation. - Injury to the sympathetic trunk typically leads to **Horner's syndrome** (ptosis, miosis, anhidrosis). *Phrenic nerve* - The **phrenic nerve** courses over the anterior scalene muscle, lateral to the thyroid gland and major vessels, making it relatively safe during standard thyroid surgery. - Damage to the phrenic nerve would result in **diaphragmatic paralysis** and respiratory compromise. *External branch of superior laryngeal nerve* - The **external branch of the superior laryngeal nerve (EBSLN)** is located more superiorly, running with the superior thyroid artery to the cricothyroid muscle. - Injury to the EBSLN would affect the **pitch of the voice** but is less commonly injured during inferior thyroid artery ligation compared to the RLN.
Question 8: A 50-year-old smoker presents with hoarseness, dysphagia, and weight loss. Flexible laryngoscopy shows a mass on the vocal cords. What is the next best step?
- A. Direct laryngoscopy with biopsy (Correct Answer)
- B. MRI of neck
- C. CT scan of neck
- D. Radiotherapy
Explanation: ***Direct laryngoscopy with biopsy*** - A definitive diagnosis of a vocal cord mass requires **histological examination** to rule out malignancy, especially given the patient's risk factors (age, smoking) and symptoms (hoarseness, dysphagia, weight loss). - **Direct laryngoscopy** allows for a thorough, magnified view of the mass and precise biopsy collection, which is superior to flexible laryngoscopy alone for definitive diagnosis and staging. *MRI of neck* - While MRI can provide excellent soft tissue detail for **staging** a known malignancy, it cannot provide a **histological diagnosis**. - It would typically be performed after a biopsy confirms malignancy to assess the extent of the tumor and potential spread. *CT scan of neck* - A CT scan is useful for evaluating **bony involvement**, lymph node status, and tumor extension for **staging purposes**, but it is not a diagnostic tool for identifying the specific type of tissue or cell pathology. - Like MRI, a CT scan would generally follow a biopsy confirming malignancy. *Radiotherapy* - **Radiotherapy** is a treatment modality for laryngeal cancer, not a diagnostic step. - Initiating treatment without a definitive histological diagnosis of malignancy would be inappropriate and potentially harmful.
Question 9: A 45-year-old patient presents with persistent hoarseness for 3 months. Which finding on indirect laryngoscopy is most concerning for malignancy?
- A. Reinke's edema
- B. Unilateral cord paralysis (Correct Answer)
- C. Bilateral polyps
- D. Vocal cord nodules
Explanation: ***Unilateral cord paralysis*** - **Unilateral cord paralysis** can be an indicator of an underlying malignancy impinging on the **recurrent laryngeal nerve**, which innervates the vocal cords. - The **persistent hoarseness** for 3 months, combined with paralysis, raises significant concern for a malignant process in the head, neck, or chest. *Reinke's edema* - **Reinke's edema** is typically associated with **chronic irritation** like smoking and presents as a swollen, gelatinous fluid collection in the superficial lamina propria. - While it causes hoarseness, it is a **benign condition** and not directly indicative of malignancy. *Bilateral polyps* - **Vocal cord polyps** are typically **benign lesions** often caused by vocal trauma or abuse, and while they can cause hoarseness, they are not usually a direct sign of malignancy, especially when bilateral. - While requiring management, polyps themselves do **not raise immediate concern for cancer** compared to paralysis. *Vocal cord nodules* - **Vocal cord nodules** (singer's nodules) are benign, bilateral lesions caused by **vocal abuse** and are a common cause of hoarseness. - They are a benign condition and do not suggest an underlying malignancy at their core.
Question 10: Emergency tracheostomy is not indicated in
- A. Bilateral vocal cord paralysis
- B. Foreign body larynx
- C. Acute severe asthma (Correct Answer)
- D. Stridor due to laryngeal growth
Explanation: ***Acute severe asthma*** - While life-threatening, acute severe asthma is primarily managed with **bronchodilators**, **steroids**, and potentially **non-invasive or invasive ventilation**. - **Tracheostomy** is generally reserved for situations involving upper airway obstruction that cannot be managed by other means, which is not the primary issue in asthma. *Bilateral vocal cord paralysis* - This condition can cause severe **upper airway obstruction** due to the adduction of both vocal cords. - In an emergency setting, a tracheostomy may be life-saving to bypass the obstructed larynx. *Foreign body larynx* - An obstructing **foreign body in the larynx** can lead to immediate and complete airway compromise. - If efforts like the **Heimlich maneuver** or direct laryngoscopy with removal fail, an emergency tracheostomy might be necessary. *Stridor due to laryngeal growth* - A laryngeal growth causing **stridor** indicates significant airway narrowing, which can acutely worsen and lead to respiratory distress. - In cases of severe or rapidly progressive obstruction, an **emergency tracheostomy** is needed to secure the airway below the level of the growth.
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