Basic Dermatology Practice Questions

Q: Where does nevus simplex commonly present?

Face. ***Face*** - Nevus simplex, also known as a **stork bite**, **angel's kiss**, or **salmon patch**, commonly presents on the face, particularly on the eyelids, glabella, and nuchal area. - These are **capillary malformations** that are present at birth and often fade within the first few years of life. *Trunk* - While other birthmarks can appear on the trunk, nevus simplex has a very strong predilection for the **head and neck region**. - Vascular lesions on the trunk are more likely to be other types, such as infantile hemangiomas, which have a different clinical course. *Legs* - Nevus simplex is **rarely found on the legs**. - Birthmarks on the legs would more typically suggest a different etiology or pattern of vascular malformation. *Hands* - Nevus simplex is **uncommon on the hands**. - Other types of vascular lesions or dermatological conditions might affect the hands but not typically a nevus simplex.

Q: A known case of diabetes develops annular orange skin lesions that disappear after a biopsy. What is the term used to describe this phenomenon?

Reverse Koebner's phenomenon. ***Reverse Koebner's phenomenon*** - This phenomenon describes the **improvement or disappearance of skin lesions** at sites of trauma or biopsy, in contrast to the typical Koebner phenomenon where trauma induces new lesions. - In **necrobiosis lipoidica diabeticorum**, a condition associated with diabetes, annular orange lesions may temporarily resolve after trauma, which is characteristic of the reverse Koebner's phenomenon. *Koebner's phenomenon* - Also known as the **isomorphic phenomenon**, it involves the development of **new skin lesions** characteristic of a dermatosis at sites of trauma (e.g., psoriasis, lichen planus, vitiligo). - This is the opposite of what is described in the question, where lesions disappear after biopsy. *Asboe-Hansen sign* - Refers to the **extension of a blister** into previously unaffected skin when pressure is applied to the top of the blister. - This sign is typically observed in **blistering skin conditions** such as pemphigus and bullous pemphigoid, and is unrelated to the resolution of lesions after biopsy. *Isotopic phenomenon* - Describes the manifestation of a **new skin disease** at the site of a prior, unrelated, and already healed skin disease (e.g., herpes zoster followed by lichen planus in the same dermatome). - This phenomenon is not characterized by the disappearance of existing lesions following trauma.

Q: What is the typical duration for pityriasis rosea to resolve?

6-12 weeks. ***6-12 weeks*** - **Pityriasis rosea** is a self-limiting skin condition that typically resolves spontaneously within **6-8 weeks**, though it may take up to 12 weeks in some cases. - The disease progression involves a **herald patch** (present in 50-90% of cases) followed by a generalized secondary eruption that gradually fades over this timeframe. - Most authoritative dermatology texts cite this as the **standard duration** for complete resolution. *1-2 weeks* - This duration is **far too short** for pityriasis rosea, as the secondary rash typically takes 1-2 weeks just to fully develop after the herald patch. - Complete resolution in this timeframe would be extremely unusual and should prompt consideration of alternative diagnoses. *2-4 weeks* - This timeframe is still **too short** for typical resolution, as most patients are still in the active phase of the eruption at 4 weeks. - This might represent the time from herald patch to peak of eruption, not complete resolution. *4-8 weeks* - While some mild cases may begin to resolve around 6-8 weeks, this range is generally considered the **minimum duration** rather than the typical course. - Most standard dermatology references cite 6-8 weeks to 12 weeks as the expected timeframe for complete resolution.

Q: Sebaceous cysts can occur in all the following locations in the body except:

Palms and soles. ***Palms and soles*** - **Sebaceous cysts** (more accurately termed epidermoid cysts) arise from the **epidermis and hair follicle infundibulum**, not from sebaceous glands themselves. - The **palms and soles** lack both sebaceous glands and hair follicles, making these locations impossible for sebaceous cysts to form. - This is a key anatomical distinction used in clinical diagnosis. *Axilla* - The **axilla** contains numerous hair follicles and sebaceous glands, making it a common site for sebaceous cyst formation. - These cysts can become inflamed or infected due to the moist environment, friction, and bacterial flora of the region. - Hormonal influences can also contribute to cyst development in this area. *Back* - The **back** is a very common location for sebaceous cysts due to a high concentration of hair follicles and sebaceous glands. - Cysts in this area can become quite large and are often subject to irritation from clothing. - The back (especially upper back) is one of the most frequent sites for these lesions. *Pubic area* - The **pubic area** is rich in hair follicles and sebaceous glands, making it susceptible to the formation of sebaceous cysts. - **Hormonal activity** and friction can contribute to the development of these cysts in this region. - Inflammation and infection are more common in this area due to occlusion and moisture.

Q: 1 to 2 mm haemorrhages in skin are known as:

Petechiae. ***Petechiae*** - **Petechiae** are small, pinpoint (<3 mm) hemorrhages into the skin or mucous membranes. - They arise from the leakage of blood from small capillaries, often due to **platelet disorders** or **capillary fragility**. *Micro bleed* - A **micro bleed** typically refers to a small area of bleeding within the brain, detected by neuroimaging, not a skin hemorrhage. - The term is used in the context of brain imaging findings, often associated with **cerebral amyloid angiopathy** or hypertension. *Purpura* - **Purpura** are larger areas of hemorrhage into the skin, typically ranging from 3 mm to 1 cm. - They are caused by similar mechanisms as petechiae but involve a larger volume of extravasated blood, often coalescing to form visible patches. *None of the options* - This option is incorrect because **Petechiae** accurately describes 1-2 mm hemorrhages in the skin.

Q: Which glands are primarily affected by Fox Fordyce Disease?

Apocrine glands. ***Apocrine glands*** - Fox-Fordyce disease is also known as **apocrine miliaria**, directly implicating **apocrine glands** in its pathology. - The disease involves the occlusion of **apocrine duct openings**, leading to rupture of the duct and accumulation of secretory products, causing inflammation and characteristic pruritic papules. *Sebaceous glands* - These glands secrete **sebum** and are primarily affected in conditions like **acne vulgaris** or **sebaceous cysts**, not Fox-Fordyce disease. - While sebaceous glands are present in areas where Fox-Fordyce disease can occur, they are not the primary target of the disease process. *Eccrine Glands* - **Eccrine glands** produce **sweat** for thermoregulation and are affected in conditions like **miliaria crystallina** or **hyperhidrosis**. - Their involvement in Fox-Fordyce disease is secondary or negligible, as the primary pathology is distinct to apocrine structures. *Any gland* - Fox-Fordyce disease specifically targets **apocrine glands**, making a generalized involvement of "any gland" incorrect. - It does not show a predilection for **eccrine** or **sebaceous glands**; the pathology is precise.

Q: Which skin condition is characterized by a 'Christmas tree' appearance?

Pityriasis rosea. ***Pityriasis rosea*** - This condition classically presents with an eruption of oval, erythematous, slightly scaly papules and plaques arranged in a **'Christmas tree' pattern** along the skin cleavage lines on the trunk. - It often begins with a single larger lesion known as a **'herald patch'** before the generalized eruption. *Pityriasis rubra pilaris* - Characterized by reddish-orange scaling plaques with **follicular papules** and often involves confluence, leading to areas of normal skin called **'islands of sparing.'** - It does not typically form a 'Christmas tree' pattern; instead, it tends to spread cranially from the lower body. *Psoriasis* - Psoriasis typically presents as well-demarcated, erythematous plaques covered with **silvery scales**, often found on extensor surfaces, scalp, and nails. - The distinctive pattern of psoriasis does not involve a 'Christmas tree' distribution; it's more often characterized by symmetrically distributed lesions. *Vitiligo* - Vitiligo is a pigmentary disorder characterized by **depigmented macules and patches** of varying sizes, resulting from the destruction of melanocytes. - It does not involve inflammatory lesions or any specific 'Christmas tree' arrangement.

Q: Identify the skin condition depicted in the image.

Ichthyosis. ***Ichthyosis*** - The image clearly displays widespread **dry, scaling, and thickened skin**, consistent with the characteristic presentation of ichthyosis. - This condition is characterized by a defect in **skin barrier function** leading to excessive dryness and accumulation of scales. *Syndromic ichthyosis* - While syndromic ichthyosis also involves skin scaling, it is associated with **additional systemic symptoms** or **organ involvement**, which cannot be determined from this image alone. - The term "ichthyosis" broadly covers this appearance, and without more clinical information, specifying it as syndromic is not the most direct identification. *Leprosy* - Leprosy typically presents with **hypopigmented, anesthetic skin patches** or **nodules**, which are not seen in the image. - The texture and color changes in the image are not characteristic of the primarily neurological and dermatological manifestations of leprosy. *Cutaneous sarcoidosis* - Cutaneous sarcoidosis manifests as **reddish-brown papules, plaques, or nodules**, often on the face, neck, or extremities. - The widespread, fine scaling and dryness seen in the image do not align with the typical granulomatous lesions of sarcoidosis.

Q: Which of the following statements is true regarding Acanthosis Nigricans?

Is associated with insulin resistant diabetes mellitus.. ***Is associated with insulin resistant diabetes mellitus.*** - **Acanthosis nigricans** is a common cutaneous marker of **insulin resistance**, frequently seen in patients with **type 2 diabetes mellitus** or prediabetes. - The increased insulin levels stimulate **keratinocyte** and **fibroblast growth factors**, leading to the characteristic skin changes. *Is characterized by hypopigmentation.* - Acanthosis nigricans is characterized by **hyperpigmentation**, presenting as dark, velvety patches, not hypopigmentation. - The darkening of the skin is due to increased melanin production and epidermal thickening. *Commonly occurs in individuals who are lean and thin.* - While it can occur in lean individuals, acanthosis nigricans is **most commonly associated with obesity** and being overweight. - The strong link to **insulin resistance** means it is more prevalent in individuals with higher body mass indices. *Is not typically associated with skin malignancy.* - This statement is **incorrect** - acanthosis nigricans **can be associated with malignancy** as a **paraneoplastic syndrome**, particularly when it has an abrupt onset, rapid progression, or atypical distribution. - It is most commonly associated with **gastrointestinal adenocarcinomas** (e.g., stomach, colon) and sometimes lung or breast cancer.

Q: Cutis marmorata occurs due to exposure to –

Cold temperature. ***Cold temperature*** - **Cutis marmorata** is a physiological response to **cold temperatures**, characterized by a mottled, reticulated vascular pattern on the skin. - This occurs due to **vasoconstriction** of the small arteries and arterioles, alongside **vasodilation** of the venules, creating the characteristic marbled appearance. *Dust* - Exposure to **dust** typically causes **irritation**, allergic reactions, or respiratory issues, such as **dermatitis**, **contact urticaria**, or **asthma**. - It does not directly lead to the characteristic vascular changes seen in cutis marmorata. *Hot temperature* - **Hot temperatures** generally cause **vasodilation** in the skin to facilitate **heat dissipation**, leading to redness and warmth. - This is the opposite physiological response to cutis marmorata, which involves vasoconstriction. *Humidity* - **Humidity** primarily affects **skin hydration** and the rate of perspiration, potentially exacerbating certain skin conditions like **eczema** or **fungal infections**. - High or low humidity does not directly induce the vascular changes that result in cutis marmorata.

Question 1

Where does nevus simplex commonly present?

Accepted Answer

Face

Answer

Trunk

Answer

Legs

Answer

Hands

Question 2

A known case of diabetes develops annular orange skin lesions that disappear after a biopsy. What is the term used to describe this phenomenon?

Accepted Answer

Reverse Koebner's phenomenon

Answer

Koebner's phenomenon

Answer

Asboe-Hansen sign

Answer

Isotopic phenomenon

Question 3

What is the typical duration for pityriasis rosea to resolve?

Accepted Answer

6-12 weeks

Answer

1-2 weeks

Answer

2-4 weeks

Answer

4-8 weeks

Question 4

Sebaceous cysts can occur in all the following locations in the body except:

Accepted Answer

Palms and soles

Answer

Back

Answer

Pubic area

Answer

Axilla

Question 5

1 to 2 mm haemorrhages in skin are known as:

Accepted Answer

Petechiae

Answer

Micro bleed

Answer

Purpura

Answer

None of the options

Question 6

Which glands are primarily affected by Fox Fordyce Disease?

Accepted Answer

Apocrine glands

Answer

Sebaceous glands

Answer

Eccrine glands

Answer

Any gland

Question 7

Which skin condition is characterized by a 'Christmas tree' appearance?

Accepted Answer

Pityriasis rosea

Answer

Pityriasis rubra pilaris

Answer

Psoriasis

Answer

Vitiligo

Question 8

Identify the skin condition depicted in the image.

Accepted Answer

Ichthyosis

Answer

Syndromic ichthyosis

Answer

Cutaneous sarcoidosis

Answer

Leprosy

Question 9

Which of the following statements is true regarding Acanthosis Nigricans?

Accepted Answer

Is associated with insulin resistant diabetes mellitus.

Answer

Is characterized by hypopigmentation.

Answer

Commonly occurs in individuals who are lean and thin.

Answer

Is not typically associated with skin malignancy.

Question 10

Cutis marmorata occurs due to exposure to –

Accepted Answer

Cold temperature

Answer

Dust

Answer

Hot temperature

Answer

Humidity

Basic Dermatology — MCQs

Basic Dermatology — MCQs

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