Tertiary and Quaternary Structures Practice Questions

Question 1

Most abundant collagen in the body is

Accepted Answer

Type I

Answer

Type II

Answer

Type V

Answer

Type VI

Question 2

Which of the following statements about protein denaturation is correct?

Accepted Answer

The primary structure of the protein is unaffected.

Answer

Biological properties are retained after denaturation.

Answer

Denaturation is always irreversible.

Answer

Denaturation never results in proteins becoming insoluble.

Question 3

False regarding Alzheimer's disease (AD) is:

Accepted Answer

Extracellular inclusion (lesion) can occur in the absence of intracellular inclusions to make pathological diagnosis of AD

Answer

Number of neurofibrillary tangles is associated with the severity of dementia

Answer

Number of senile (neuritic) plaques correlates (increases) with age

Answer

Presence of tau protein suggest neurodegeneration

Question 4

Abnormal accumulation of misfolded protein is seen in?

Accepted Answer

Creutzfeldt-Jakob disease

Answer

Nephritic syndrome

Answer

Sickle cell anemia

Answer

Megaloblastic anemia

Question 5

Size of fibrillary proteins in amyloidosis is:

Accepted Answer

7.5-10 nm

Answer

0-5 nm

Answer

12-17 nm

Answer

18-20 nm

Question 6

Oxygen dissociation curve shifts to the right in:

Accepted Answer

Hypercarbia

Answer

Hypothermia

Answer

Metabolic alkalosis

Answer

Fetal hemoglobin (HbF) presence

Question 7

Which of the following statements about chaperones is false?

Accepted Answer

Are lipid in nature

Answer

Cause folding of proteins

Answer

Include heat shock proteins

Answer

May have ATPase activity

Question 8

A pregnant woman is able to transfer oxygen to her fetus because fetal hemoglobin has a greater affinity for oxygen than does adult hemoglobin. Why is the affinity of fetal hemoglobin for oxygen higher?

Accepted Answer

Fetal hemoglobin binds 2,3-BPG with fewer ionic bonds than the adult form.

Answer

There is less 2,3-BPG in the fetal circulation as compared to maternal circulation

Answer

The tense form of hemoglobin is more prevalent in the circulation of the fetus

Answer

The oxygen-binding curve of fetal hemoglobin is shifted to the right.

Question 9

Which type of bond is primarily responsible for the primary structure of a protein?

Accepted Answer

Peptide bond

Answer

Hydrogen bond

Answer

Disulfide bond

Answer

Electrostatic bond

Question 10

Which of the following is a type of covalent bond?

Accepted Answer

Disulfide bond

Answer

Hydrogen bond

Answer

Ionic bond

Answer

Electrostatic bond

Tertiary and Quaternary Structures — MCQs

Tertiary and Quaternary Structures — MCQs

Want unlimited practice?