Liver as Metabolic Hub Practice Questions

Question 1

Dietary cholesterol is transported from the intestine to the liver by:

Accepted Answer

Apo-B

Answer

Apo-E

Answer

Apo-A

Answer

Apo-C

Question 2

What is the primary role of Cytochrome P450 enzymes in the liver?

Accepted Answer

Oxidation of drugs

Answer

Lipid transport

Answer

Carbohydrate synthesis

Answer

Protein degradation

Question 3

In type I diabetes, which of the following is the MOST characteristic metabolic change that distinguishes it from type II diabetes:-

Accepted Answer

Increased lipolysis

Answer

Increased protein catabolism

Answer

Decreased glucose uptake

Answer

Increased hepatic glucose output

Question 4

Ammonia in brain is trapped by

Accepted Answer

Glutamine

Answer

Alanine

Answer

Aspartate

Answer

Ornithine

Question 5

Which of the following statements about LDL is false?

Accepted Answer

Transports maximum amount of lipid

Answer

More dense than chylomicron

Answer

Contains maximum cholesterol

Answer

Smaller than VLDL

Question 6

Which of the following statements about gluconeogenesis is true?

Accepted Answer

Uses ATP

Answer

Occurs only in liver

Answer

Activated by insulin

Answer

Uses only lactate as a substrate

Question 7

What happens to glucose consumed in a soft drink by a 19-year-old athlete during a track event?

Accepted Answer

Muscles will primarily use glucose for immediate energy production.

Answer

Hexokinase helps convert glucose to energy quickly during exercise.

Answer

The glucose from the soda will be stored as glycogen in the liver.

Answer

Glucose will be used by both muscles and liver.

Question 8

Ketone body formation without glycosuria is seen in ?

Accepted Answer

Starvation

Answer

Diabetes mellitus

Answer

Diabetes insipidus

Answer

Obesity

Question 9

Which of the following is not a ketone body produced by the liver?

Accepted Answer

Glycerol 3-phosphate

Answer

Acetone

Answer

β-hydroxybutyrate

Answer

Acetoacetate

Question 10

Which enzyme deficiency is responsible for Hyperammonemia type-1?

Accepted Answer

Carbamoyl phosphate synthetase I (CPS-1) deficiency

Answer

Arginase deficiency

Answer

Arginosuccinate lyase deficiency

Answer

Arginosuccinate synthase deficiency

Liver as Metabolic Hub — MCQs

Liver as Metabolic Hub — MCQs

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