Ribozymes and Catalytic RNA Practice Questions

Question 1

During eukaryotic protein synthesis, phosphorylation of which of the following is enhanced by insulin?

Accepted Answer

eIF4E

Answer

eIF2

Answer

eIF4A

Answer

eIF4G

Question 2

Which of the following is a function of ribozymes?

Accepted Answer

Peptidyl transferase activity

Answer

Cut DNA at specific site

Answer

GTPase activity

Answer

Participate in DNA synthesis

Question 3

Which type of RNA is primarily involved in gene silencing?

Accepted Answer

miRNA

Answer

rRNA

Answer

tRNA

Answer

mRNA

Question 4

Which RNA is used in RNA splicing?

Accepted Answer

Small nuclear RNA (snRNA)

Answer

mRNA

Answer

tRNA

Answer

rRNA

Question 5

Which condition is associated with defects in pre-mRNA splicing and SMN protein dysfunction?

Accepted Answer

Spinal muscular atrophy

Answer

Sickle cell disease

Answer

Huntington's disease

Answer

α-Thalassemia

Question 6

Kcat/Km is a measure of which of the following?

Accepted Answer

Enzyme efficiency

Answer

Speed of enzymatic reaction

Answer

Concentration of substrate

Answer

Enzyme turnover

Question 7

Carboxypeptidase contains which mineral?

Accepted Answer

Zinc

Answer

Copper

Answer

Iron

Answer

None of the options

Question 8

Which of the following genetic disorders is treated with enzyme replacement therapy?

Accepted Answer

Gaucher's disease

Answer

Krabbe's disease

Answer

Metachromatic leukodystrophy

Answer

Tay-Sachs disease

Question 9

Which statement is false about allosteric regulation?

Accepted Answer

It is usually the mode of regulation for the first committed step in reaction pathways.

Answer

Cellular response is faster with allosteric control than by controlling enzyme concentration in the cell.

Answer

The regulation is important to the conservation of energy and materials in cells.

Answer

Allosteric modulators bind non-covalently at sites other than the active site and induce conformational changes in the enzyme.

Question 10

Non-competitive inhibition is:

Accepted Answer

Any of the above

Answer

Reversible

Answer

Irreversible

Answer

None of the above

Ribozymes and Catalytic RNA — MCQs

Ribozymes and Catalytic RNA — MCQs

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