Molecular Mechanisms in Development Practice Questions

Question 1

Ewing's sarcoma is characterized by:

Accepted Answer

Small round blue cell tumor with CD99 positivity

Answer

Osteoid formation by malignant cells

Answer

Cartilage matrix production

Answer

Giant cell proliferation

Question 2

The labia majora develop from which embryological structure?

Accepted Answer

Labioscrotal swellings

Answer

Urogenital folds

Answer

Müllerian ducts

Answer

Genital tubercle

Question 3

What is the pattern of inheritance in neural tube defects?

Accepted Answer

Multifactorial inheritance

Answer

Autosomal recessive

Answer

X-linked dominant

Answer

Autosomal dominant

Answer

X-linked recessive

Question 4

Holt-Oram syndrome is caused by a mutation of?

Accepted Answer

TBX5

Answer

NKX2.5

Answer

Lefty

Answer

None of the options

Question 5

Which of the following statements provides the MOST COMPLETE description of sclerotome function during vertebral development?

Accepted Answer

The sclerotome surrounds the notochord and the neural tube during development.

Answer

The notochord forms the nucleus pulposus.

Answer

The sclerotome contributes to the formation of vertebral bodies.

Answer

The sclerotome surrounds the notochord.

Question 6

Left-Right movement of skull occurs at:-

Accepted Answer

Atlanto-axial joint

Answer

C6-C7

Answer

C2-C3

Answer

Atlanto-occipital joint

Question 7

Just before birth, which epiphysis appears?

Accepted Answer

Lower end of femur

Answer

Upper end of humerus

Answer

Lower end of fibula

Answer

Upper end of tibia

Question 8

Remnants of Wolffian ducts in a female are found in

Accepted Answer

Broad ligament

Answer

Uterovesical pouch

Answer

Pouch of Douglas

Answer

Iliac fossa

Question 9

During embryological development, failure of the urorectal septum to completely separate the cloaca results in which of the following congenital anomalies?

Accepted Answer

Persistent cloaca

Answer

Imperforate anus

Answer

Cloacal exstrophy

Answer

Rectovaginal fistula

Question 10

The tonsils are derived from:

Accepted Answer

2nd branchial pouch

Answer

1st branchial pouch

Answer

3rd branchial pouch

Answer

4th branchial pouch

Molecular Mechanisms in Development — MCQs

Molecular Mechanisms in Development — MCQs

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