INI-CET 2022 — Psychiatry

Q: Which of the following is false about bipolar disorder?

Unipolar mania is more common than bipolar disorder. ***Unipolar mania is more common than bipolar disorder*** - This statement is **false** because **unipolar mania is extremely rare**, while **bipolar disorder (which includes both manic and depressive episodes)** is significantly more common. - **Unipolar mania** refers to recurrent manic episodes without any depressive episodes, a presentation that is seldom observed clinically. *Genetic factors play important role* - This statement is **true**, as **bipolar disorder has a strong genetic component**, with **heritability estimated between 60-80%**. - **First-degree relatives** of individuals with bipolar disorder are at a significantly higher risk of developing the condition. *Rapid cycling is more common in females* - This statement is **true**; **rapid cycling (4 or more mood episodes per year)** occurs more frequently in females with bipolar disorder. - **Women with bipolar disorder** are also more likely to experience **mixed features** and **more depressive episodes** compared to males. *Age of onset is earlier than unipolar depression* - This statement is **true** because the **typical age of onset for bipolar disorder is in early adulthood (late teens to early 20s)**, whereas **unipolar depression often has a later average onset**, though both can occur at any age. - An earlier age of onset in bipolar disorder is linked to poorer prognosis and more severe illness course. [Practice more Psychiatry PYQs on OnCourse]

Q: Match the following: 1. Kleptomania 2. Pyromania 3. Mutilomania 4. Dipsomania A. Intense desire to drink alcoholic drinks B. Intense desire to mutilate C. Intense desire to steal items of trivial value D. Intense desire to burn things

1-C, 2-D, 3-B, 4-A. **1-C, 2-D, 3-B, 4-A** - **Kleptomania** is characterized by an **irresistible urge to steal objects** that are often of little value and not needed for personal use or monetary gain. - **Pyromania** involves a **preoccupation with fire** and an overwhelming urge to set fires and witness their effects. - **Mutilomania** is a rare impulse control disorder that involves an **intense desire to self-mutilate**. - **Dipsomania** describes an **uncontrollable craving for alcohol**, leading to recurrent bouts of excessive drinking. *1-C, 2-B, 3-D, 4-A* - This option incorrectly matches Pyromania with an intense desire to mutilate and Mutilomania with an intense desire to burn things. - **Pyromania** is specifically about fire, and **Mutilomania** is about self-harm. *1-D, 2-B, 3-A, 4-C* - This option incorrectly matches Kleptomania with the desire to burn things, Pyromania with the desire to mutilate, and Dipsomania with the desire to steal. - The core definitions of these terms are not aligned in this pairing. *1-D, 2-C, 3-B, 4-A* - This option incorrectly matches Kleptomania with the desire to burn things and Pyromania with the desire to steal. - The defining characteristics of these impulse control disorders are mismatched here. [Practice more Psychiatry PYQs on OnCourse]

Q: A 14-year-old girl presented with sudden-onset blindness for the past 4 hours. However, on history taking, it is noted that she is not concerned about it. However, she is concerned that her mother passed away recently and that she should have spent more time with her. Physical examination findings are normal. Which of the following is true about the condition?

In children, it occurs more in females than in males. **In children, it occurs more in females than in males** - **Conversion disorders** (functional neurological symptom disorder) are more prevalent in **females** across childhood, adolescence, and adulthood. - The patient's **sudden-onset blindness** without medical cause, coupled with a lack of concern (**la belle indifférence**) and a psychological stressor (mother's death), points to a conversion disorder, which aligns with higher female prevalence in this age group. *In adults, equally among males and females* - This statement is incorrect as conversion disorders, including sudden-onset blindness, are generally more common in **adult females** than males. - The prevalence in adults is not equal; there is a clear gender disparity, with women being more affected. *In children, equally among males and females* - While it can occur in both sexes, the prevalence of conversion disorder in children is not equal; it is observed more frequently in **females**. - Studies consistently report a female-to-male ratio greater than 1 in pediatric populations. *In adults, it occurs more in males than in females* - This statement is incorrect; in adults, conversion disorders are significantly more common in **females**. - The classic presentation, as seen in this case, fits the typical profile observed in female patients experiencing significant psychological distress. [Practice more Psychiatry PYQs on OnCourse]

Q: A 29 year old lady came to psychiatry OPD with symptoms of hypomania. She has a past history of manic episode. Now, she is planning to conceive. Which drug should be avoided for being highly teratogenic to the fetus?

Valproate. ***Valproate*** - **Valproate** is highly **teratogenic** and is associated with multiple birth defects, including **neural tube defects** (e.g., spina bifida), cardiac anomalies, and craniofacial defects. - Due to its significant risks, it is generally **contraindicated** in women of childbearing potential, especially during pregnancy, unless no other suitable alternatives exist. *Oxcarbazepine* - While it has some teratogenic risk (e.g., cleft palate), the risk is generally considered **lower than valproate**. - It is often favored over valproate in pregnant women requiring mood stabilizers, but still requires careful risk-benefit assessment. *Lithium* - **Lithium** is associated with an increased risk of **Ebstein's anomaly**, a specific cardiac defect, if used during the first trimester. - However, the overall risk of major malformations is still **lower than valproate**, and it can be used with careful monitoring if other options are not viable. *Olanzapine* - **Olanzapine** is an **atypical antipsychotic** that can be used as a mood stabilizer and is considered to have a **relatively lower teratogenic risk** compared to anticonvulsants like valproate. - While it's not entirely risk-free (associated with gestational diabetes and fetal growth issues), it's often a safer option in pregnancy for bipolar disorder than valproate. [Practice more Psychiatry PYQs on OnCourse]

4 Previous Year Questions with Answers & Explanations

Questions

Which of the following is false about bipolar disorder?

Match the following: 1. Kleptomania 2. Pyromania 3. Mutilomania 4. Dipsomania A. Intense desire to drink alcoholic drinks B. Intense desire to mutilate C. Intense desire to steal items of trivial value D. Intense desire to burn things

A 14-year-old girl presented with sudden-onset blindness for the past 4 hours. However, on history taking, it is noted that she is not concerned about it. However, she is concerned that her mother passed away recently and that she should have spent more time with her. Physical examination findings are normal. Which of the following is true about the condition?

A 29 year old lady came to psychiatry OPD with symptoms of hypomania. She has a past history of manic episode. Now, she is planning to conceive. Which drug should be avoided for being highly teratogenic to the fetus?

INI-CET 2022 - Psychiatry INI-CET Practice Questions and MCQs

Question 1: Which of the following is false about bipolar disorder?

A. Unipolar mania is more common than bipolar disorder (Correct Answer)
B. Genetic factors play important role
C. Rapid cycling is more common in females
D. Age of onset is earlier than unipolar depression

Explanation: ***Unipolar mania is more common than bipolar disorder*** - This statement is **false** because **unipolar mania is extremely rare**, while **bipolar disorder (which includes both manic and depressive episodes)** is significantly more common. - **Unipolar mania** refers to recurrent manic episodes without any depressive episodes, a presentation that is seldom observed clinically. *Genetic factors play important role* - This statement is **true**, as **bipolar disorder has a strong genetic component**, with **heritability estimated between 60-80%**. - **First-degree relatives** of individuals with bipolar disorder are at a significantly higher risk of developing the condition. *Rapid cycling is more common in females* - This statement is **true**; **rapid cycling (4 or more mood episodes per year)** occurs more frequently in females with bipolar disorder. - **Women with bipolar disorder** are also more likely to experience **mixed features** and **more depressive episodes** compared to males. *Age of onset is earlier than unipolar depression* - This statement is **true** because the **typical age of onset for bipolar disorder is in early adulthood (late teens to early 20s)**, whereas **unipolar depression often has a later average onset**, though both can occur at any age. - An earlier age of onset in bipolar disorder is linked to poorer prognosis and more severe illness course.

Question 2: Match the following: 1. Kleptomania 2. Pyromania 3. Mutilomania 4. Dipsomania A. Intense desire to drink alcoholic drinks B. Intense desire to mutilate C. Intense desire to steal items of trivial value D. Intense desire to burn things

A. 1-C, 2-B, 3-D, 4-A
B. 1-D, 2-B, 3-A, 4-C
C. 1-D, 2-C, 3-B, 4-A
D. 1-C, 2-D, 3-B, 4-A (Correct Answer)

Explanation: **1-C, 2-D, 3-B, 4-A** - **Kleptomania** is characterized by an **irresistible urge to steal objects** that are often of little value and not needed for personal use or monetary gain. - **Pyromania** involves a **preoccupation with fire** and an overwhelming urge to set fires and witness their effects. - **Mutilomania** is a rare impulse control disorder that involves an **intense desire to self-mutilate**. - **Dipsomania** describes an **uncontrollable craving for alcohol**, leading to recurrent bouts of excessive drinking. *1-C, 2-B, 3-D, 4-A* - This option incorrectly matches Pyromania with an intense desire to mutilate and Mutilomania with an intense desire to burn things. - **Pyromania** is specifically about fire, and **Mutilomania** is about self-harm. *1-D, 2-B, 3-A, 4-C* - This option incorrectly matches Kleptomania with the desire to burn things, Pyromania with the desire to mutilate, and Dipsomania with the desire to steal. - The core definitions of these terms are not aligned in this pairing. *1-D, 2-C, 3-B, 4-A* - This option incorrectly matches Kleptomania with the desire to burn things and Pyromania with the desire to steal. - The defining characteristics of these impulse control disorders are mismatched here.

Question 3: A 14-year-old girl presented with sudden-onset blindness for the past 4 hours. However, on history taking, it is noted that she is not concerned about it. However, she is concerned that her mother passed away recently and that she should have spent more time with her. Physical examination findings are normal. Which of the following is true about the condition?

A. In adults, equally among males and females
B. In children, it occurs more in females than in males (Correct Answer)
C. In children, equally among males and females
D. In adults, it occurs more in males than in females

Explanation: **In children, it occurs more in females than in males** - **Conversion disorders** (functional neurological symptom disorder) are more prevalent in **females** across childhood, adolescence, and adulthood. - The patient's **sudden-onset blindness** without medical cause, coupled with a lack of concern (**la belle indifférence**) and a psychological stressor (mother's death), points to a conversion disorder, which aligns with higher female prevalence in this age group. *In adults, equally among males and females* - This statement is incorrect as conversion disorders, including sudden-onset blindness, are generally more common in **adult females** than males. - The prevalence in adults is not equal; there is a clear gender disparity, with women being more affected. *In children, equally among males and females* - While it can occur in both sexes, the prevalence of conversion disorder in children is not equal; it is observed more frequently in **females**. - Studies consistently report a female-to-male ratio greater than 1 in pediatric populations. *In adults, it occurs more in males than in females* - This statement is incorrect; in adults, conversion disorders are significantly more common in **females**. - The classic presentation, as seen in this case, fits the typical profile observed in female patients experiencing significant psychological distress.

Question 4: A 29 year old lady came to psychiatry OPD with symptoms of hypomania. She has a past history of manic episode. Now, she is planning to conceive. Which drug should be avoided for being highly teratogenic to the fetus?

A. Oxcarbazepine
B. Lithium
C. Olanzapine
D. Valproate (Correct Answer)

Explanation: ***Valproate*** - **Valproate** is highly **teratogenic** and is associated with multiple birth defects, including **neural tube defects** (e.g., spina bifida), cardiac anomalies, and craniofacial defects. - Due to its significant risks, it is generally **contraindicated** in women of childbearing potential, especially during pregnancy, unless no other suitable alternatives exist. *Oxcarbazepine* - While it has some teratogenic risk (e.g., cleft palate), the risk is generally considered **lower than valproate**. - It is often favored over valproate in pregnant women requiring mood stabilizers, but still requires careful risk-benefit assessment. *Lithium* - **Lithium** is associated with an increased risk of **Ebstein's anomaly**, a specific cardiac defect, if used during the first trimester. - However, the overall risk of major malformations is still **lower than valproate**, and it can be used with careful monitoring if other options are not viable. *Olanzapine* - **Olanzapine** is an **atypical antipsychotic** that can be used as a mood stabilizer and is considered to have a **relatively lower teratogenic risk** compared to anticonvulsants like valproate. - While it's not entirely risk-free (associated with gestational diabetes and fetal growth issues), it's often a safer option in pregnancy for bipolar disorder than valproate.