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A young patient presents with persistently elevated blood pressure despite adequate lifestyle measures. Laboratory evaluation reveals hypokalemia associated with metabolic alkalosis. There is no history of diuretic intake, and renal function tests are within normal limits. Which of the following is the most likely diagnosis?
A patient was detected to have a medullary carcinoma of thyroid and has a family history of endocrine tumors, and genetic counseling is advised. The clinician plans further evaluation to identify associated inherited syndromes and guide family screening. Which of the following statements regarding this condition is correct?
A middle-aged woman presents with long -standing complaints of dryness of eyes and mouth, requiring frequent use of artificial tears and water while swallowing food. She also reports generalized pruritus and intermittent pain with stiffness in multiple small joints of the hands, suggestive of inflammatory arthritis. There is no history of skin tightening, Raynaud phenomenon, oral ulcers, or photosensitive rash. Based on this clinical presentation, what is the most likely diagnosis?
A middle-aged male presents to the OPD with complaints of vague abdominei discomfort, intermittent diarrhea, and recent weight loss. There is no history of alcohol intake or gallstone disease. MRI abdomen reveals a diffusely enlarged c pancreas with a characteristic "sausage- shaped" appearance. Laboratory evaluation shows markedly elevated serum IGG4 Tevels. Which of the following is the best treatment for this patient?
A 60-year-old female presents with chronic breathlessness and cough for several years, which has progressively worsened. She has a significant smoking history of 30 pack-years. There is no history of atopy. Pulmonary function testing shows a post-bronchodilator FEV/FVC ratio of <0.7 with an 18% improvement in FEV1 after bronchodilator administration. CXR is shown below?
A 17-year-old boy presents with gradually progressive muscle weakness predominantly involving the proximal muscles of the lower limbs. He has difficulty climbing stairs and getting up from a squatting position. There is a significant family history and his elder brother had similar complaints and died around the age of 40 years. Based on the age of onset, pattern of inheritance, and survival, what is the most likely diagnosis?
A 65 year old man presents with sudden onset weakness of the left upper and lower limbs and slurred speech which started 2 hours ago. MRI of the brain is shown in the image. Which of the following is the most appropriate initial management?
What is the suspected acid-base disorder based on the ABG analysis? pH 7.45 PaCO2 28 mmHg HCO3 20mEq/L
A 35-year-old man presents with high-grade fever, severe myalgia (predominantly calf pain), and redness of eyes for the last 4 days. He gives a history of wading through flood water one week ago. On examination, conjunctival suffusion is noted. There isno jaundice or renal impairment at present. This clinical presentation most likely corresponds to which phase of leptospirosis?
A 35-year-old man presents with headache and neck stiffness for 5 days. Lumbar puncture reveals the following CSF findings: 90% lymphocytes and 10% neutrophils with CSF glucose: 40 mg/dL (Plasma glucose: 100mg/dL), protein is 1 gm/dl. What is the most likely diagnosis?