Definition and calculation of relative risk - Risk Rundown
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Relative Risk (RR): Compares the risk of developing a disease in the exposed group versus the unexposed group. It's the ratio of incidence in the exposed to incidence in the unexposed.
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Calculation Formula:
- The risk of disease in the exposed group is $a/(a+b)$.
- The risk of disease in the unexposed group is $c/(c+d)$.
- $RR = [a/(a+b)] / [c/(c+d)]$
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Interpretation:
- RR > 1: Exposure increases the risk of disease.
- RR < 1: Exposure decreases the risk of disease (protective).
- RR = 1: No association between exposure and disease.
⭐ Relative risk is the primary measure of association in cohort studies, as these studies track incidence over time.
High‑Yield Points - ⚡ Biggest Takeaways
- Relative Risk (RR) is the ratio of the incidence of an outcome in the exposed group to the incidence in the unexposed group.
- It is the preferred measure of association for cohort studies and randomized controlled trials (RCTs).
- The formula is [a/(a+b)] / [c/(c+d)].
- RR = 1 indicates no association between the exposure and the outcome.
- RR > 1 suggests an increased risk of the outcome in the exposed group.
- RR < 1 implies a decreased risk (protective effect) from the exposure.
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