Sick Day Rules - Weathering the Storm
📌 SICK Day Mnemonic:
- Sugar: Check blood glucose frequently (q2-4h).
- Insulin: Never stop basal insulin. May need ↑ supplemental doses.
- Carbs & Fluids: Maintain hydration and carb intake. If unable to eat, drink carb-containing fluids.
- Ketones: Monitor urine/blood ketones q4h, especially if glucose is >250 mg/dL.
⭐ The most common precipitating factor for DKA is infection (e.g., UTI, pneumonia), which increases counter-regulatory hormones and insulin demand.
Monitoring - Know Your Numbers
-
Blood Glucose (BG):
- Check every 2-4 hours when sick.
- Log readings, insulin doses, and symptoms.
- Call your provider if BG remains > 250 mg/dL despite corrective insulin.
-
Ketones:
- Check every 4-6 hours if BG is > 250 mg/dL or you feel ill.
- Urine: Positive result (moderate/large) is a warning sign.
- Blood (β-hydroxybutyrate): Preferred method for accuracy.
- Normal: < 0.6 mmol/L
- Call provider if > 1.5 mmol/L

⭐ Blood ketone (β-hydroxybutyrate) testing is more accurate than urine testing for diagnosing and monitoring DKA. Urine acetoacetate levels can lag, remaining positive even after DKA begins to resolve.
Insulin & Meds - The Lifeline
- Never Stop Insulin: The most common cause of DKA is insulin non-adherence. Emphasize continuing basal (long-acting) insulin even when ill.
- 📌 SICK Day Rules:
- Sugar: Check blood glucose more frequently (q 2-4h).
- Insulin: Continue basal insulin. Use supplemental short-acting insulin for hyperglycemia.
- Carbs: Maintain adequate fluid and carbohydrate intake.
- Ketones: Check urine or blood for ketones if glucose is >250 mg/dL.

⭐ A patient's basal insulin requirement persists and is crucial to suppress ketogenesis, even with zero oral intake. Never advise stopping it.
Diet & Hydration - Fueling Right
- Consistent Carb Intake: Match carbohydrate intake with insulin doses. Regular meals and snacks prevent blood sugar lows that can lead to poor food choices.
- Hydration is Key: Drink plenty of water and calorie-free fluids. Dehydration can concentrate blood glucose and increase ketone production.
- Sick Day Management: Never stop insulin. Maintain hydration and carb intake with liquids if solid food isn't tolerated (e.g., juice, broth, gelatin).
⭐ Dehydration itself worsens hyperglycemia and impairs the kidney's ability to clear glucose and ketones, accelerating the progression to DKA.
High-Yield Points - ⚡ Biggest Takeaways
- Sick day management is crucial: never stop taking insulin, even with poor oral intake. Monitor glucose and ketones frequently.
- Maintain hydration, alternating between sugar-free and sugar-containing fluids depending on glucose levels.
- Emphasize strict insulin adherence as the primary prevention strategy.
- Know when to seek help: persistent vomiting, high fever, or glucose >250 mg/dL with ketones.
- Recognize and manage DKA triggers like infection, stress, and missed insulin doses.
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