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Refractive Surgery

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Refractive Errors & Candidacy - Setting the Stage

  • Refractive Errors:
    • Myopia: Focus before retina; concave (-) lens.
    • Hyperopia: Focus behind retina; convex (+) lens.
    • Astigmatism: Multiple foci; cylindrical lens.
    • Presbyopia: Age-related ↓ accommodation.
  • Candidacy Essentials: (📌 S.A.F.E.R.)
    • Stable Refraction: <0.5D change/ ≥1 yr.
    • Age: ≥18 yrs (ideally >21).
    • Favourable Corneal Thickness (CT): Adequate (LASIK: pre-op ~500µm, RSB ≥250-300µm).
    • Expectations: Realistic.
    • Robust Health: No active ocular/uncontrolled systemic disease.
    • (Not pregnant/lactating). Light focus in myopia, hyperopia, and astigmatism

⭐ Absolute Contraindications: Keratoconus, active autoimmune disease, unrealistic expectations, severe dry eye.

Laser Vision Correction - Zapping to Clarity

Laser vision correction reshapes the cornea. Common types: LASIK, PRK, SMILE.

  • Mechanism: Excimer laser (LASIK, PRK) ablates cornea; Femtosecond laser creates SMILE lenticule.
  • Munnerlyn Formula: $t = S^2 \times D / 3$ ($t$=ablation depth, $S$=optical zone, $D$=diopters).
  • Key Thresholds: Residual Stromal Bed (RSB) > 250-300 µm. LASIK flap: 100-120 µm.
FeatureLASIK (Laser-Assisted In Situ Keratomileusis)PRK (Photorefractive Keratectomy)SMILE (Small Incision Lenticule Extraction)
FlapYes (Femto/Microkeratome, 100-120 µm)NoNo (Cap, not a full flap)
EpitheliumPreserved under flapRemoved (Alcohol/Mechanical)Minimally disturbed
PainMinimal, 1-2 daysModerate, 3-5 daysMinimal, 1 day
Visual RecoveryRapid (1 day)Slower (1-2 weeks)Rapid (1-3 days)
Dry EyesCommon, often transientLess common than LASIKPotentially least
Haze RiskLowHigher (esp. high myopia), Mitomycin C usedVery Low
Corneal BiomechanicsReduced due to flapBetter preservedBest preserved
Suited ForWide rangeThin corneas, contact sportsMyopia, astigmatism, contact sports

Exam Favourite: Most common LASIK complication: dry eye syndrome.

Lens-Based & Incisional Options - Alternative Routes

  • Phakic IOLs (PIOLs): Implanted lenses, natural lens retained.

    • Indications: High myopia/hyperopia, astigmatism; laser unsuitable.
    • Key Req: Anterior Chamber Depth (ACD) >2.8 mm (posterior), >3.0-3.2 mm (anterior); adequate Endothelial Cell Count (ECC).
    • Types:
      TypeLocationFixationExamples
      AnteriorAnt. ChamberAngle/Iris-clawCachet, Artisan
      PosteriorPost. ChamberSulcusICL (Visian/EVO)
    • Complications: Endothelial loss, cataract, glaucoma, pigment dispersion.
    • Posterior Chamber Phakic IOL Placement

    ⭐ Phakic IOLs preserve accommodation & are reversible; key for high myopia, avoiding excessive corneal ablation.

  • Refractive Lens Exchange (RLE/CLE): Clear lens replaced with IOL.

    • Indications: High errors, presbyopia, early cataract.
    • Pros: Definitive, premium IOLs. Cons: Loses accommodation (monofocal), surgical risks.
  • Incisional Keratotomy (AK/LRIs): Corneal incisions for astigmatism.

    • Uses: Native or post-op astigmatism.
    • Note: Less predictable than laser methods.

Post-Op & Complications - The Aftermath

  • Post-Op Regimen:
    • Topical steroids (e.g., Prednisolone) & antibiotics (e.g., Moxifloxacin) tapered.
    • Frequent preservative-free artificial tears.
    • Protective eyewear.
  • Complications:
    • Early: Dry eye, flap striae, Diffuse Lamellar Keratitis (DLK), infection.
    • Late: Regression, haze (PRK > LASIK), corneal ectasia, epithelial ingrowth.

DLK "Sands of Sahara" post-LASIK

ComplicationManagement Highlights
Dry EyeLubricants, Punctal Plugs
Flap StriaeObserve or Flap lift & reposition/stretch
DLK↑Steroids; Flap lift & irrigation (severe)
Epithelial IngrowthObserve or Debridement ± MMC
%%{init: {'flowchart': {'htmlLabels': true}}}%%
flowchart TD

Start["👁️ Flap Striae
• Post-LASIK finding• Corneal wrinkles"]

Decision["📋 Assessment
• Visual impact?• Check symptoms"]

Monitor["👁️ Monitoring
• Observe progress• Routine follow-up"]

Treatment["💊 Flap Repair
• Lift and reposition• Stretch the flap"]

Outcome["✅ Assess Result
• Check VA levels• Resolution status"]

Start --> Decision Decision -->|No| Monitor Decision -->|Yes| Treatment Treatment --> Outcome

style Start fill:#F7F5FD, stroke:#F0EDFA, stroke-width:1.5px, rx:12, ry:12, color:#6B21A8 style Decision fill:#FEF8EC, stroke:#FBECCA, stroke-width:1.5px, rx:12, ry:12, color:#854D0E style Monitor fill:#EEFAFF, stroke:#DAF3FF, stroke-width:1.5px, rx:12, ry:12, color:#0369A1 style Treatment fill:#F1FCF5, stroke:#BEF4D8, stroke-width:1.5px, rx:12, ry:12, color:#166534 style Outcome fill:#F6F5F5, stroke:#E7E6E6, stroke-width:1.5px, rx:12, ry:12, color:#525252


> ⭐ Corneal ectasia: most feared long-term complication. Risk factors: thin residual stromal bed (<**300**µm), high myopia, abnormal pre-op topography. 

##  High‑Yield Points - ⚡ Biggest Takeaways

> * **LASIK**: **Corneal flap** for excimer ablation. **PRK**: **Epithelium removed**, then **stromal surface ablation**.
> * **SMILE**: **Flapless**; femtosecond laser creates intrastromal **lenticule**, then extracted.
> * **Wavefront/Topography-guided** ablations reduce **higher-order aberrations** (HOAs) for better vision quality.
> * Commonest side effect: **Dry eye**. Most serious risk: **Corneal ectasia** (maintain **Residual Stromal Bed**).
> * Ideal candidates: Age >**18 years**, **stable refraction** (≥1 year), adequate **corneal thickness** & topography.
> * Contraindications: **Keratoconus**, **thin corneas**, **unstable refraction**, active ocular/systemic inflammation.

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