Appendicitis

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Appendicitis: Anatomy & Etiopathogenesis - Gut's Grumpy Nook

  • Anatomy Essentials:
    • True diverticulum of caecum; base at confluence of 3 taeniae coli.
      • 📌 Mnemonic: "Taeniae meet At The Appendix base."
    • Surface marking: McBurney's point (junction of lateral ⅓ & medial ⅔, umbilicus to ASIS line).
    • Most common position: Retrocaecal (~65-70%). Others: pelvic, subcaecal, pre/post-ileal.
    • Blood supply: Appendicular artery (end-artery from ileocolic artery).
    • Innervation: Sympathetic & visceral afferents via T10 (initial periumbilical pain).
  • Etiopathogenesis:
    • Core mechanism: Luminal obstruction.
      • Adults: Fecolith (most common).
      • Children: Lymphoid hyperplasia (most common).
      • Others: Parasites (e.g., Ascaris), carcinoid tumor, foreign body, strictures.
    • Pathophysiology Cascade:
*   ![Anatomy of the appendix and surrounding structures](https://ylbwdadhbcjolwylidja.supabase.co/storage/v1/object/public/notes/L1/Surgery_Gastrointestinal_Surgery_Appendicitis/3f12c452-bf96-4a7c-8b4a-24514bd2ff6e.jpg)
> ⭐ The lifetime risk of developing appendicitis is approximately **7-8%**. 

Appendicitis: Clinical Features - Pain's Pointed March

  • Pain Trajectory (Classic):
    • Onset: Dull, periumbilical, colicky (visceral).
    • Migration (📌 "Pointed March"): To Right Iliac Fossa (RIF) within 12-24 hrs.
    • Character: Sharp, constant, localized at McBurney's point.
  • Key Associated Symptoms:
    • Anorexia: Often first, highly consistent.
    • Nausea/Vomiting: Typically after pain onset.
    • Fever: Low-grade (< 38.5°C).
  • Physical Exam Signs:
    • RIF tenderness, guarding, rebound.
    • Special Tests: Rovsing's, Psoas, Obturator signs positive. McBurney's point and appendix location

⭐ The sequence of symptoms is crucial: anorexia, then vague abdominal pain, then vomiting, then localization of pain to RIF and fever development (Dieulafoy's triad for sequence: pain, nausea/vomiting, fever).

Appendicitis: Diagnosis & DDx - Case of the Coded Clues

  • Clinical Scoring:
    • Alvarado Score (MANTRELS - Migratory RIF pain, Anorexia, Nausea/Vomiting, Tenderness RIF, Rebound, Elevated temp, Leukocytosis, Shift to left): Max 10.
      • Score ≤4: Appendicitis unlikely.
      • Score 5-6: Equivocal → Image.
      • Score ≥7: High probability → Surgery consult.
    • Appendicitis Inflammatory Response (AIR) Score: Max 12. Similar interpretation.
  • Lab Tests:
    • ↑WBC (Neutrophilia, left shift).
    • ↑C-Reactive Protein (CRP).
  • Imaging:
    • Ultrasound (USG): First-line in children & pregnant women. Appendix diameter >6mm, non-compressible, target sign, appendicolith. Ultrasound of appendix and iliac vessels
    • Contrast-Enhanced CT (CECT) Abdomen: Gold standard. Dilated appendix >6mm, wall thickening, peri-appendiceal fat stranding, appendicolith.

      ⭐ CECT abdomen has a sensitivity and specificity of >95% for acute appendicitis.

  • Differential Diagnosis (DDx):
    • Gastrointestinal: Mesenteric adenitis, Meckel's diverticulitis, Crohn's disease, diverticulitis.
    • Gynecological: Ectopic pregnancy, Pelvic Inflammatory Disease (PID), ovarian torsion/cyst rupture.
    • Urological: Ureteric colic, Pyelonephritis/UTI.
  • Diagnostic Pathway:

Appendicitis: Management & Complications - Snip, Stitch, Sidestep

  • Initial Steps: NPO, IV fluids, analgesia, broad-spectrum IV antibiotics (e.g., Ceftriaxone + Metronidazole).
  • Definitive Management:
    • Appendectomy: Gold standard.
      • Laparoscopic: Preferred; ↓pain, ↓stay, faster recovery.
      • Open: McBurney’s or Lanz incision.
    • Non-Operative Management (NOM): For selected uncomplicated cases with antibiotics. Recurrence risk ~20-30% within 1 year.
  • Specific Scenarios:
    • Appendicular Mass: Initial conservative (Ochsner-Sherren regime). Consider interval appendectomy after 6-8 weeks.
    • Appendicular Abscess: Percutaneous drainage + antibiotics. If drainage fails/unavailable → surgery. ⭐ > The most common overall complication following appendectomy is wound infection.

Laparoscopic Appendectomy Set-up and Procedure

  • Key Complications:
    • Perforation (esp. extremes of age)
    • Wound Infection (most common)
    • Intra-abdominal/Pelvic Abscess
    • Stump Appendicitis
    • Adhesive Small Bowel Obstruction (late)
    • Portal Pyemia (septic pylephlebitis - rare)

High‑Yield Points - ⚡ Biggest Takeaways

  • McBurney's point tenderness is the most reliable clinical sign.
  • Alvarado score (MANTRELS) aids diagnosis; score ≥7 strongly suggests appendicitis.
  • USG is initial imaging (children/pregnant); CT scan is most accurate for adults.
  • Perforation is the most common serious complication, leading to peritonitis.
  • Standard treatment is appendectomy (laparoscopic preferred).
  • Obturator and Psoas signs may indicate a retrocecal appendix.
  • Key DDx: mesenteric adenitis, ectopic pregnancy, PID, Meckel's diverticulitis.

Practice Questions: Appendicitis

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A patient with right lower quadrant pain shows target sign on ultrasound. Diagnosis?

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Flashcards: Appendicitis

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The Fold of _____ is an antimesenteric ileocecal fold of peritoneum used as a guide while coagulating vessels in the mesoappendix

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The Fold of _____ is an antimesenteric ileocecal fold of peritoneum used as a guide while coagulating vessels in the mesoappendix

Treves

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