Appendicitis in Children

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Intro & Pathophysiology - Genesis of Gut Grief

  • Appendicitis: Acute inflammation of the vermiform appendix.
  • Most common non-traumatic pediatric surgical emergency; peak incidence 10-19 years.
  • Pathogenesis: Initiated by obstruction of the appendiceal lumen, leading to a cascade.
    • Children: Lymphoid hyperplasia (60-70%, often post-viral URI) is the primary culprit.
    • Other causes: Fecaliths, inspissated stool, parasites (e.g., Ascaris), foreign bodies, rarely tumors.

Causes of Appendicitis: Fecalith and Lymphoid Hyperplasia

⭐ Lymphoid follicular hyperplasia in the submucosa is the most frequent cause of luminal obstruction in children, distinguishing it from adult appendicitis where fecaliths are more common (accounting for ~60% of pediatric cases).

Clinical Picture - Tiny Tummy Troubles

  • Classic Sequence: Periumbilical pain → migrates to RIF (McBurney's point).
  • Associated Symptoms:
    • Anorexia (highly consistent).
    • Nausea & Vomiting (typically after pain onset).
    • Fever (low-grade, ↑ if perforated).
  • Key Physical Signs:
    • Localized RIF tenderness, guarding.
    • Rebound tenderness.
    • Rovsing's sign (pain in RIF on LLQ palpation).
    • Psoas/Obturator signs (retrocecal/pelvic appendix).
  • Age-Specifics:
    • Infants/Young Children (<5 yrs): Atypical; diffuse pain, irritability, vomiting, diarrhea. Higher perforation risk.

McBurney's point location

⭐ Younger children (<5 yrs) present atypically, leading to delayed diagnosis and ↑ perforation rates (e.g., 80-100% in neonates).

Diagnostic Drilldown - Spotting the Sneak

  • Clinical Scoring Systems:
    • Alvarado Score (📌 MANTRELS): Score > 7 highly indicative.
    • Pediatric Appendicitis Score (PAS): Score > 6 high risk. Key: RLQ tenderness, cough/hop pain, N/V, anorexia, fever >38°C, WBC >10k, PMN >7.5k.
  • Imaging Modalities:
    • Ultrasound (USG): Preferred initial imaging.
      • Appendix diameter > 6mm.
      • Non-compressible, aperistaltic.
      • Wall thickening, "target sign".
      • Free fluid, appendicolith.
    • CT Scan: If USG equivocal or suspected complications. Higher accuracy, radiation risk.
    • MRI: Alternative to CT; no radiation.

Ultrasound: Normal vs. Appendicitis

⭐ The Pediatric Appendicitis Score (PAS) is often preferred over Alvarado in children due to its higher specificity and validation in pediatric populations.

Treatment Tactics - Eviction Notice!

  • Appendectomy: Mainstay. Laparoscopic preferred (↓pain, ↓LOS). Open for complex cases. Laparoscopic appendectomy steps
  • Antibiotics (ABX): 📌 "APPendicitis ABX": Pre-op, Post-op.
    • Pre-op: Broad-spectrum (e.g., Cefoxitin, Gentamicin+Metronidazole).
    • Post-op:
      • Non-perforated: Stop within 24 hrs.
      • Perforated/Gangrenous: IV for 3-7 days.
  • Non-Operative Management (NOM): For select, stable, uncomplicated cases (antibiotics alone).
  • Complicated (Abscess/Phlegmon):
    • Initial: IV ABX, bowel rest, +/- percutaneous drainage (abscess > 3-4 cm).
    • Interval Appendectomy: 6-8 weeks later (controversial).
  • Management Flow:

⭐ Interval appendectomy after successful NOM for complicated appendicitis reduces recurrence risk (10-20%) and allows histological diagnosis.

Complications & DDx - Watch Outs!

  • Perforation (common, esp. <5 yrs)
  • Abscess (pelvic, appendiceal)
  • Phlegmon
  • Sepsis
  • Wound infection
  • Late: Adhesive bowel obstruction
DDxFeatures
Mesenteric adenitisURI hx, diffuse pain, USG nodes
GastroenteritisDiarrhea, vomiting precedes pain
UTIDysuria, pyuria
IntussusceptionColicky pain, red currant jelly stool
Meckel's diverticulitisMimics appendicitis; painless bleed (classic)

High‑Yield Points - ⚡ Biggest Takeaways

  • Appendicitis is the most common surgical emergency in children.
  • Younger children (<5 years) often have atypical presentations, ↑ risk of perforation.
  • Classic symptoms: periumbilical pain migrating to RIF, vomiting, and fever.
  • McBurney's point tenderness is a crucial diagnostic sign.
  • Pediatric Appendicitis Score (PAS) or Alvarado score aids clinical diagnosis.
  • Ultrasound is the preferred initial imaging; CT for equivocal cases.
  • Treatment is appendectomy (laparoscopic preferred) and appropriate antibiotics.

Practice Questions: Appendicitis in Children

Test your understanding with these related questions

An infant presents with colicky pain and vomiting, along with a sausage-shaped lump in the abdomen, and the diagnosis is:

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Flashcards: Appendicitis in Children

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_____ is characterized by dilation of the stomach and proximal duodenum with a "double bubble" sign on X-ray

TAP TO REVEAL ANSWER

_____ is characterized by dilation of the stomach and proximal duodenum with a "double bubble" sign on X-ray

Duodenal atresia

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