Traumatic Brain Injury

Traumatic Brain Injury

Traumatic Brain Injury

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TBI Introduction - Brainy Bruises

TBI Primary and Secondary Injury and Neurological Deficits

  • Definition: Acquired brain injury from external mechanical force, impairing cognitive, physical, or psychosocial functions.
  • Types:
    • Primary: Occurs at impact (e.g., skull fracture, contusion, laceration, DAI).
    • Secondary: Evolves post-impact (systemic: hypoxia, hypotension; intracranial: ↑ICP, edema); exacerbates damage.
  • Pediatric Causes:
    • Falls (most common, esp. <2 yrs).
    • MVAs (leading TBI death cause).
    • Sports injuries.
    • NAT/AHT (significant morbidity).
  • Epidemiology:
    • Major cause of death & disability in children >1 yr.
    • Peaks: <5 yrs & 15-19 yrs.
    • Boys > Girls.
  • High-Yield:

    Growing skull fracture (leptomeningeal cyst): rare in infants. Dural tear beneath fracture allows herniation, prevents healing, causes progressive enlargement.

Clinical Assessment - Spotting Trouble

  • Primary Survey (ABCDE): Rapidly assess Airway, Breathing, Circulation, Disability (GCS, pupils), Exposure.
  • History: Mechanism (e.g., fall >3ft or 5 stairs if <2y, >5ft if ≥2y), LOC duration, amnesia, seizures, vomiting (≥3 episodes).
  • Examination Findings:
    • Vitals: Cushing's triad (late sign: ↑BP, ↓HR, irregular respirations).
    • Head: Scalp hematoma/laceration, palpable fracture, Battle's sign (mastoid ecchymosis), Raccoon eyes (periorbital ecchymosis).
    • Fontanelle (infants): Bulging, tense.
    • Neuro: Pediatric GCS (PGCS), pupillary asymmetry/reactivity, focal deficits, posturing.
  • Age-Specific Signs:
    • Infants: Persistent irritability, lethargy, poor feeding, high-pitched cry.
    • Children: Headache, dizziness, amnesia, visual changes.
  • Severity (PGCS): Mild (13-15), Moderate (9-12), Severe (≤8).

    ⭐ A drop in GCS by ≥2 points is a critical sign of neurological worsening requiring urgent intervention.

  • Red Flags: Deteriorating GCS, new/worsening focal neurological signs, persistent vomiting, seizures, signs of skull fracture.

Imaging & Diagnosis - Peeking Inside

  • Initial Choice: Non-contrast CT (NCCT) head is the primary imaging modality for acute TBI.
  • CT Indications (PECARN 📌):
    • Age <2 yrs: GCS <15, palpable skull Fx, LOC >5s, non-frontal scalp hematoma, severe mechanism.
    • Age ≥2 yrs: GCS <15, basilar skull Fx signs, LOC, vomiting, severe headache, severe mechanism.
  • MRI: Superior for non-accidental injury (NAI), persistent neurological deficits despite normal CT, or assessing late sequelae like Diffuse Axonal Injury (DAI).
  • Skull X-ray: Limited role; CT preferred for brain injury assessment.
  • Lesion Types: Epidural (EDH), Subdural (SDH), Subarachnoid (SAH), Intracerebral, Diffuse Axonal Injury (DAI).

Pediatric EDH on CT and MRI

⭐ Epidural hematoma (EDH) classically presents with a "lucid interval" before neurological deterioration.

Management Principles - Healing Heads

  • Initial Stabilization (ABCDE):
    • Airway: Intubate if GCS ≤ 8.
    • Breathing: Oxygenation.
    • Circulation: Maintain MAP; avoid hypotension.
    • Disability: GCS, pupils.
    • Exposure: Normothermia.
  • ICP Monitoring: If GCS ≤ 8 & abnormal CT. Target ICP < 20 mmHg.
  • Raised ICP Management (Tiered):
    • Tier 0: Head elevation 30° (midline), analgesia/sedation.
    • Tier 1: Mannitol (0.25-1 g/kg) OR Hypertonic Saline (3% 2-5 ml/kg); CSF drainage.
    • Tier 2: Mild hyperventilation (PaCO₂ 30-35 mmHg); optimize CPP (50-70 mmHg).
    • Tier 3: Barbiturate coma, decompressive craniectomy.

⭐ Cushing's Triad (hypertension, bradycardia, irregular respirations) is a LATE, ominous sign of severely ↑ICP & impending herniation.

High‑Yield Points - ⚡ Biggest Takeaways

  • Glasgow Coma Scale (GCS) is crucial for assessment; use Pediatric GCS for non-verbal children.
  • Suspect Non-Accidental Trauma (NAT) with findings like subdural hematomas, retinal hemorrhages, or inconsistent history.
  • Cushing's triad (hypertension, bradycardia, irregular breathing) signals critically elevated Intracranial Pressure (ICP).
  • Management prioritizes preventing secondary brain injury: optimize oxygenation, perfusion; avoid hypotension and hypoxia.
  • Mannitol or 3% hypertonic saline are first-line for acute ↑ ICP; consider decompressive craniectomy if refractory.

Practice Questions: Traumatic Brain Injury

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First step in management of raised intracranial pressure-

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Flashcards: Traumatic Brain Injury

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Microcephaly is defined as an occipitofrontal circumference more than _____ SD below the mean for age and sex.

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Microcephaly is defined as an occipitofrontal circumference more than _____ SD below the mean for age and sex.

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