Complications of Cataract Surgery

Complications of Cataract Surgery

Complications of Cataract Surgery

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Intraoperative Complications - Surgery Slip-ups

  • Wound Issues:
    • Poor construction (leak, astigmatism), thermal burn.
    • Descemet's Membrane Detachment (DMD): Instrument trauma.
    • Iris Prolapse: Poor wound apposition, ↑IOP.
  • Capsular Events:
    • Posterior Capsular Rupture (PCR): High risk: vitreous loss, dropped nucleus/IOL.
    • Zonular Dialysis: Weak zonules (pseudoexfoliation); IOL instability.
    • Argentinian Flag Sign: Anterior capsular tear extension (intumescent cataracts).
  • Nucleus/Cortex Problems:
    • Dropped Nucleus/Fragments: May need PPV (pars plana vitrectomy).
    • Retained Cortex: Post-op inflammation (uveitis).
  • IOL Related:
    • IOL Decentration/Tilt: Poor sizing, asymmetric fixation.
    • IOL Damage (optic scratch, haptic bend): During insertion.
    • Incorrect IOL power.
  • Hemorrhage:
    • Suprachoroidal Hemorrhage (Expulsive): Acute massive bleed; rock-hard eye, loss of red reflex, pain.

      ⭐ Expulsive suprachoroidal hemorrhage: most dreaded intraoperative complication, high risk of severe, permanent vision loss.

    • Hyphema: Iris/ciliary body vessel bleed.
  • Miscellaneous:
    • Corneal Endothelial Damage: Excessive phaco energy/time, instrument touch.
    • Vitreous Loss: From PCR/zonular dialysis; meticulous anterior vitrectomy vital.

Early Postoperative Complications - Quick Comebacks

  • Corneal Edema:
    • Causes: Surgical trauma, ↑IOP, pre-existing endothelial dystrophy.
    • Rx: Hypertonic saline, topical steroids, IOP control. Often self-limiting. Slit lamp view of corneal edema
  • Wound Leak:
    • Signs: Shallow Anterior Chamber (AC), ↓IOP, positive Seidel's test.
    • Rx: Bandage contact lens (BCL), aqueous suppressants, resuturing if severe.
  • Shallow/Flat AC:
    • Causes: Wound leak, pupillary block, ciliochoroidal detachment, suprachoroidal hemorrhage.
    • Rx: Address cause; cycloplegics, steroids, surgical intervention.
  • Elevated Intraocular Pressure (IOP):
    • Causes: Retained viscoelastic, inflammation (trabeculitis), steroid response, pupillary block.
    • Rx: Anti-glaucoma medications (topical/systemic), AC paracentesis.
  • Hyphema:
    • Rx: Rest, head elevation (30-45°), cycloplegics, topical steroids, IOP control. Avoid NSAIDs.
  • Toxic Anterior Segment Syndrome (TASS):
    • Sterile, non-infectious inflammation, typically 12-48 hours post-op. Diffuse limbus-to-limbus corneal edema, significant AC reaction.
    • Rx: Intensive topical corticosteroids.

    ⭐ TASS is a sterile inflammatory reaction to intraocular substances, presenting 12-48 hours post-surgery with diffuse corneal edema and anterior chamber inflammation. Crucially differentiated from infectious endophthalmitis.

  • Early Endophthalmitis:
    • Signs: Severe pain, ↓vision, hypopyon, marked AC reaction, vitritis. Usually 2-7 days post-op.
    • Rx: URGENT. Intravitreal antibiotics ± diagnostic/therapeutic vitrectomy.
  • Retained Lens Matter (RLM):
    • Signs: Persistent uveitis, ↑IOP, corneal edema, cystoid macular edema.
    • Rx: Medical (topical steroids, NSAIDs, IOP control); surgical removal if significant/refractory inflammation.

Late Postoperative Complications - Long-Term Loops

  • Posterior Capsular Opacification (PCO)
    • Most common; proliferation of lens epithelial cells (LECs) → Elschnig pearls, Soemmering ring.
    • Symptoms: ↓ Vision, glare.
    • Tx: Nd:YAG laser capsulotomy. Elschnig pearls and posterior capsular opacification
  • Cystoid Macular Edema (CME) - Late/Chronic Irvine-Gass Syndrome
    • Persistent or recurrent months post-op.
    • Risks: Diabetes, uveitis, complicated surgery.
    • Tx: Topical NSAIDs/steroids; intravitreal anti-VEGF/steroids if refractory.
  • Intraocular Lens (IOL) Issues
    • Decentration/Dislocation: Zonular weakness, capsular phimosis, trauma.
    • IOL Opacification: Glistenings (common, usually benign), calcification (rare, visually significant).
    • Uveitis-Glaucoma-Hyphema (UGH) Syndrome: IOL chafing iris/ciliary body.
  • Secondary Glaucoma
    • Steroid-induced, pupillary block (adhesions, IOL malposition), UGH Syndrome.
  • Chronic Postoperative Endophthalmitis
    • Low-grade infection (e.g., P. acnes, fungi).
    • Symptoms: Mild, persistent uveitis, white plaque on IOL/capsule.
    • Tx: Intravitreal antibiotics, possible IOL explantation.
  • Retinal Detachment (Pseudophakic RD)
    • Incidence: 0.5-2%. Higher risk in myopia, intraoperative posterior capsular rent.
    • Symptoms: Floaters, flashes, field defect.
  • Pseudophakic Bullous Keratopathy (PBK)
    • Corneal endothelial decompensation → chronic corneal edema.
    • Risks: Pre-existing endothelial dystrophy (e.g., Fuchs'), surgical trauma.
    • Tx: Corneal transplant (DSEK/DMEK/PKP).

PCO is the most frequent late complication following cataract surgery, often managed effectively with Nd:YAG laser capsulotomy.

High‑Yield Points - ⚡ Biggest Takeaways

  • Posterior Capsular Opacification (PCO): Most common late complication; treat with Nd:YAG laser.
  • Acute Endophthalmitis: Most feared early complication (2-7 days); Staph. epidermidis common.
  • Cystoid Macular Edema (CME) / Irvine-Gass: Painless vision loss, peaks 4-12 weeks post-op.
  • Retinal Detachment: Risk ↑, especially with high myopia or posterior capsule rupture.
  • Toxic Anterior Segment Syndrome (TASS): Sterile inflammation (12-48 hours); differentiate from endophthalmitis.
  • IOL malposition/dislocation: Can cause significant visual symptoms, may need repositioning.

Practice Questions: Complications of Cataract Surgery

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In which of the following conditions does IOL implantation after cataract surgery require the greatest caution and specialized management?

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Flashcards: Complications of Cataract Surgery

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Galactosemia is associated with _____ cataract

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Galactosemia is associated with _____ cataract

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