Postpartum Complications

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Postpartum Hemorrhage - Code Red Crisis

  • Definition: Blood loss >500mL (vaginal), >1000mL (LSCS); or hemodynamic instability. Severe PPH: >2L.
  • Etiology (4 T's 📌): Tone (uterine atony, ~70-80%), Trauma (lacerations, ~20%), Tissue (retained products, ~10%), Thrombin (coagulopathy, ~1%).
  • Code Red Protocol:
    • Help: Call multidisciplinary team (obstetrician, anesthetist, blood bank).
    • ABC: Secure IV access (x2 large bore), O2, fluids, blood transfusion.
    • Uterotonics (for Atony):
      • Oxytocin 10-40 IU IV infusion.
      • Methylergometrine 0.2mg IM/IV (Contra: HTN).
      • Carboprost 0.25mg IM (Contra: Asthma).
      • Misoprostol 800-1000µg PR/SL/PO.
      • Tranexamic acid 1g IV (within 3 hrs).
    • Mechanical/Surgical: Uterine massage, Bakri balloon, B-Lynch suture, UAE, Hysterectomy.
    • Other T's: Repair trauma, remove retained tissue, correct coagulopathy.
  • Shock Index (HR/SBP): >0.9 suggests significant blood loss.

Postpartum Hemorrhage Management Algorithm

⭐ Active Management of Third Stage of Labor (AMTSL) - controlled cord traction, uterotonic (Oxytocin 10 IU IM/IV), uterine massage - reduces PPH incidence by ~60%.

Puerperal Sepsis & Infections - Fever Pitch Peril

  • Definition: Genital tract infection; from rupture of membranes (ROM)/labor up to 42 days postpartum. Fever ≥38°C (100.4°F) on any 2 of the first 10 days postpartum (excluding the first 24 hours).
  • Common Sites: Endometrium (endometritis - most common), C-section wound, perineal tear, UTI.
  • Organisms: Polymicrobial. Common: Group A & B Streptococci, E. coli, Staphylococcus aureus, anaerobes (Bacteroides, Peptostreptococcus).
  • Risk Factors: Caesarean section (highest risk), prolonged ROM (>18 hrs), prolonged labor, multiple vaginal examinations, retained products of conception (RPOC), manual removal of placenta, anemia, poor hygiene.
  • Clinical Features: Fever, chills, tachycardia, malaise, lower abdominal pain, uterine tenderness/subinvolution, foul-smelling or purulent lochia.
    • Wound infection: Local pain, erythema, warmth, swelling, discharge.
  • Diagnosis: Primarily clinical. Investigations: CBC (leukocytosis), high vaginal swab (HVS) C&S, blood cultures (if systemic signs), urine C&S. Ultrasound (USG) to rule out RPOC or abscess. Puerperal endometritis ultrasound
  • Management:
    • Prompt broad-spectrum IV antibiotics (e.g., Clindamycin + Gentamicin; Piperacillin-Tazobactam).
    • Supportive care: IV fluids, antipyretics, analgesia. Surgical drainage for abscess/infected hematoma.
  • Complications: Septic shock, pelvic abscess, septic pelvic thrombophlebitis (SPT), peritonitis, disseminated intravascular coagulation (DIC).

⭐ Endometritis is the most common cause of puerperal pyrexia, typically presenting with fever and uterine tenderness 2-3 days postpartum (but can occur up to 6 weeks).

Postpartum VTE - Clot Shot Chaos

  • Venous Thromboembolism (DVT/PE): Increased risk up to 6-12 weeks postpartum; peak in 1st week. Virchow's triad (stasis, hypercoagulability, endothelial injury) is amplified.
  • Key Risk Factors:
    • Cesarean section (especially emergency)
    • Previous VTE
    • Obesity (BMI >30 kg/m²)
    • Age >35 years
    • Prolonged immobility
    • Inherited or acquired thrombophilia
    • Major postpartum hemorrhage (>1L)
  • Deep Vein Thrombosis (DVT):
    • Symptoms: Unilateral leg pain, swelling, tenderness, warmth, redness.
    • Diagnosis: Compression ultrasonography (CUS). D-dimer has high negative predictive value if pre-test probability is low.
  • Pulmonary Embolism (PE):
    • Symptoms: Sudden onset dyspnea, pleuritic chest pain, tachycardia, tachypnea, cough, hemoptysis.
    • Diagnosis: CT Pulmonary Angiography (CTPA) is gold standard; V/Q scan if CTPA contraindicated.
  • Prevention:
    • Early ambulation for all postpartum women.
    • Prophylactic anticoagulation (e.g., LMWH Enoxaparin 40mg SC OD) for high-risk women (e.g., C-section with other risk factors).
  • Treatment:
    • Therapeutic anticoagulation: LMWH (e.g., Enoxaparin 1mg/kg SC BID or 1.5mg/kg SC OD) is preferred initially.
    • Bridge to Vitamin K antagonist (Warfarin) for long-term, target INR 2.0-3.0.
    • Duration: Minimum 3-6 months. LMWH and Warfarin are safe during breastfeeding.
  • 📌 Mnemonic for DVT signs: SWELLING (Swelling, Warmth, Erythema, Leg pain, Lack of pulse (rare), Inflammation, No symptoms (sometimes), Girth increase).

DVT Diagnosis with Compression Ultrasonography

⭐ Pulmonary embolism is a leading cause of direct maternal mortality in developed countries. The risk of VTE is highest in the first 3 weeks postpartum, particularly after Cesarean section.

Postpartum Psychiatric Disorders - Mind Over Muddle

  • Postpartum Blues (PPB):
    • Onset: 2-3 days postpartum, resolves by 2 weeks.
    • Features: Mild depression, tearfulness, irritability.
    • Tx: Reassurance, support.
  • Postpartum Depression (PPD):
    • Onset: Within 4 weeks (up to 1 yr).
    • Features: Depressed mood, anhedonia. Edinburgh Postnatal Depression Scale (EPDS) >12.
    • Tx: Psychotherapy, SSRIs.
  • Postpartum Psychosis (PPP):
    • Onset: Usually within 2 weeks. Medical emergency.
    • Features: Delusions, hallucinations, risk to self/baby.
    • Tx: Hospitalization, antipsychotics, ECT.

⭐ PPP has a high recurrence rate (~50%) in subsequent pregnancies and is often associated with bipolar disorder.

High‑Yield Points - ⚡ Biggest Takeaways

  • PPH: Most common cause is uterine atony. AMTSL is crucial for prevention.
  • Puerperal sepsis: Marked by fever >38°C postpartum; Group A Strep is key pathogen.
  • Thromboembolism (DVT/PE): Major mortality risk, explained by Virchow's triad.
  • Postpartum psychiatric issues: Distinguish common blues, depression (use EPDS), and psychosis (emergency).
  • Mastitis: Usually unilateral, S. aureus common; continue breastfeeding advised.
  • Sheehan's syndrome: Pituitary necrosis post-severe PPH; presents with lactation failure.
  • RPOC: Frequent cause of secondary PPH and infection; ultrasound confirms_diagnosis_

Practice Questions: Postpartum Complications

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A woman, who is 4 days postpartum, presented with tearfulness, mood swings, and occasional insomnia. What is the likely diagnosis?

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Flashcards: Postpartum Complications

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WHO guidelines for AMTSL include postpartum abdominal _____ assessment for early identification of uterine atony

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WHO guidelines for AMTSL include postpartum abdominal _____ assessment for early identification of uterine atony

uterine tonus

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