Postpartum Hemorrhage Management

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PPH Definition & Scope - Defining the Bleed

  • PPH: Excessive bleeding after childbirth.
  • Blood loss criteria:
    • Vaginal delivery: >500ml
    • Cesarean section: >1000ml
    • Any amount causing hemodynamic instability or a ≥10% drop in hematocrit.
  • Types by onset:
    • Primary (Early): Within 24 hours postpartum (most common).
    • Secondary (Late): From >24 hours up to 12 weeks postpartum.

⭐ PPH is a leading cause of maternal mortality, particularly in low-resource settings.

  • Clinical signs (e.g., tachycardia, hypotension) may appear before measured loss hits thresholds, especially with concealed hemorrhage.

PPH Etiology - The Four Culprits

📌 4Ts: Tone, Trauma, Tissue, Thrombin

CulpritDescriptionCommon Examples
ToneUterine Atony (most common, 70-80%)Overdistended uterus, prolonged labor, infection
TraumaGenital Tract LacerationsCervical/vaginal tears, uterine rupture, episiotomy
TissueRetained Products of Conception (RPOC)Placental fragments, membranes, blood clots
ThrombinCoagulopathy (rare, pre-existing/acquired)DIC, ITP, von Willebrand disease, anticoagulants

⭐ Uterine atony is the single most common cause of PPH, responsible for approximately 70-80% of cases.

PPH Management - Flood Control Protocol

⭐ Active Management of Third Stage of Labor (AMTSL) significantly reduces PPH incidence by over 60%.

📌 Initial Response: "HELP"

  • Help: Call multidisciplinary team (Obstetrician, Anesthetist, Blood Bank).
  • Ensure IV access (2 large-bore), send bloods (X-match, FBC, Coags).
  • Lay flat, O2, catheterize bladder.
  • Palpate uterus: Fundal massage. Identify cause (4 T's: Tone, Trauma, Tissue, Thrombin).

Stepwise Management Algorithm:

Key Interventions:

  • Uterotonics (Sequence may vary):
    • Oxytocin: 10-40 IU in $500\text{ml}$ NS IV infusion; or 10 IU IM.
    • Methylergometrine: $0.2\text{mg}$ IM/IV (slowly, ⚠️ CI: HTN, Cardiac disease).
    • Carboprost (PG F2α): $0.25\text{mg}$ IM (q15-90min, max 8 doses; ⚠️ CI: Asthma).
    • Misoprostol: $800-1000\text{mcg}$ PR/PO/SL.
  • Mechanical Tamponade:
    • Intrauterine balloon (e.g., Bakri). PPH Management Algorithm
  • Surgical:
    • Repair trauma.

    • Compression sutures (e.g., B-Lynch).

    • Arterial ligation (uterine, ovarian, internal iliac).

    • Hysterectomy (last resort).

PPH Complications - Aftermath & Alerts

  • Early Complications:
    • Shock sequelae (organ damage: ARDS, AKI)
    • Anemia (transfuse if Hb < 7 g/dL or symptomatic)
    • Infection (endometritis, sepsis): fever, uterine tenderness
    • DIC: monitor coagulation, manage cause
  • Delayed Complications:
    • Secondary PPH (>24h - 12wks): causes: retained products, infection
    • Asherman's syndrome (post-curettage)
    • Psychological sequelae (PTSD, depression)
  • Long-term:

    ⭐ Sheehan's syndrome (postpartum pituitary necrosis) is a classic, albeit rare, long-term sequela of severe PPH leading to hypovolemic shock.

  • ⚠️ Alerts:
    • Persistent/worsening bleeding despite uterotonics
    • Shock signs disproportionate to visible loss
    • Oliguria (urine output < 0.5 ml/kg/hr)
    • Altered mental status

High‑Yield Points - ⚡ Biggest Takeaways

  • Uterine atony is the leading cause of PPH, accounting for 70-80% of cases.
  • Active Management of Third Stage of Labor (AMTSL) significantly reduces PPH incidence.
  • Initial management involves bimanual uterine massage and IV oxytocin infusion.
  • Second-line uterotonics: Methylergonovine (contraindicated in hypertension), Carboprost (PGF2α, contraindicated in asthma), Misoprostol.
  • Administer Tranexamic acid (TXA) within 3 hours of birth to reduce bleeding death.
  • Consider the Four T's (Tone, Trauma, Tissue, Thrombin) for systematic etiology identification.
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The fourth stage of labour is a stage of observation for at least _____ after the full expulsion of the placenta.

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The fourth stage of labour is a stage of observation for at least _____ after the full expulsion of the placenta.

an hour

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