Goals & Scope - Setting the Stage
- Primary Goal: Enhance patient safety by minimizing perioperative morbidity and mortality.
- Core Purpose:
- Systematically identify patient-specific risk factors (e.g., comorbidities, allergies, medications).
- Optimize the patient's physiological status pre-surgery.
- Develop a tailored anesthetic and perioperative management plan.
- Scope of Assessment:
- Comprehensive medical history and focused physical examination.
- Judicious selection of preoperative investigations.
- Risk stratification to guide clinical decisions.
⭐ The primary aim of preoperative assessment is risk identification and mitigation, not merely surgical "clearance."
History & Examination - The Detective Work
- Key History:
- Surgical indication, comorbidities (cardiac, respiratory, renal, endocrine).
- Prior anesthetic issues (malignant hyperthermia, difficult airway).
- Medications (anticoagulants, antiplatelets, steroids). Note other significant drugs.
- 📌 AMPLE History:
- Allergies
- Medications (current)
- Past medical Hx (including anesthesia)
- Last meal (NPO: solids 6-8h, clear fluids 2h)
- Events leading to admission/surgery
- Exercise tolerance (>4 METs).
- Focused Examination:
- Vitals, BMI.
- Airway: Mouth opening (>3 fingers), Mallampati Score (I-IV), Thyromental Distance (TMD >6.5 cm), neck mobility, dentition.
- Systemic: Focused CVS, RS.

⭐ A thyromental distance < 6 cm, sternomental distance < 12.5 cm, or Mallampati Class III/IV often predict difficult laryngoscopy.
Risk Assessment & ASA - Grading the Challenge
-
ASA Physical Status Classification: Assesses overall patient health.
- ASA I: Normal healthy patient.
- ASA II: Mild systemic disease, no significant functional limitation.
- ASA III: Severe systemic disease, significant functional limitation.
- ASA IV: Severe systemic disease that is a constant threat to life.
- ASA V: Moribund patient not expected to survive without the operation.
- ASA VI: Declared brain-dead patient, organ procurement.
- Suffix 'E': Emergency procedure.

-
Revised Cardiac Risk Index (RCRI): Predicts Major Adverse Cardiac Events (MACE). 1 point per factor:
- High-risk surgery (e.g., vascular, intraperitoneal, intrathoracic).
- History of Ischemic Heart Disease (IHD).
- History of Congestive Heart Failure (CHF).
- History of Cerebrovascular Disease (CVA/TIA).
- Diabetes Mellitus requiring Insulin.
- Preoperative Serum Creatinine >2.0 mg/dL.
- MACE Risk: 0 pts (0.4%); 1 pt (0.9%); 2 pts (6.6%); ≥3 pts (>11%).
⭐ ASA physical status is a strong independent predictor of perioperative mortality; risk approximately doubles with each increasing class.
Fasting & Medications - Pre-Flight Checks
- NPO Guidelines (ASA): 📌 "2-4-6-8 Rule"
- Clear liquids: 2 hrs
- Breast milk: 4 hrs
- Infant formula/Light meal (toast & clear liquids): 6 hrs
- Fatty/Fried/Meat meal: 8 hrs

- Medication Management:
- Continue: β-blockers, statins, most antihypertensives (ACEi/ARBs often held day of surgery), anti-epileptics, thyroid medications.
- Hold/Adjust:
- Oral hypoglycemics: Hold AM dose.
- Insulin: Adjust (e.g., ½ to ⅔ of long-acting, hold short-acting).
- Anticoagulants: Warfarin (stop 3-5 days, target INR <1.5), DOACs (stop 1-5 days based on drug/renal function).
- Antiplatelets: Aspirin (often continued for high CV risk; stop 5-7 days if elective/high bleed risk), Clopidogrel (stop 5-7 days).
- Diuretics: Hold AM dose.
- MAOIs: Stop 2 weeks prior.
⭐ Beta-blockers should be continued perioperatively in patients chronically taking them to prevent adverse cardiac events; abrupt withdrawal can be harmful.
High‑Yield Points - ⚡ Biggest Takeaways
- ASA Physical Status Classification is key for perioperative risk stratification.
- A thorough history (medical, surgical, medications, allergies) is fundamental.
- Focused airway assessment (e.g., Mallampati) and cardiovascular examination are vital.
- Investigations must be selective, guided by clinical findings, not routine.
- Assessing functional capacity (METs) helps predict perioperative cardiac events.
- Informed consent detailing risks, benefits, and alternatives is mandatory.
- Preoperative optimization of comorbidities (e.g., diabetes, HTN) improves outcomes.
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