Basics & Bugs - Setting the Stage
- Anatomy: Pathways of Spread
- Hand's fascial planes (thenar, midpalmar) & tendon sheaths allow rapid infection spread.
- Flexor tendon sheaths: Synovial fluid aids bacterial growth; risk of proximal spread to Parona's space.

- Common Bugs & Considerations:
- Staphylococcus aureus: Most common. MRSA strains prevalent.
⭐ Staphylococcus aureus is the most common pathogen in hand infections.
- Streptococcus pyogenes: Aggressive, can cause necrotizing fasciitis.
- Polymicrobial: Frequent in bites (human: Eikenella corrodens; animal: Pasteurella multocida).
- Staphylococcus aureus: Most common. MRSA strains prevalent.
- Key Risk Factors:
- Penetrating trauma (thorns, bites).
- Diabetes Mellitus (impaired healing/immunity).
- IV Drug Use (direct inoculation). 📌 IVDU.
- Immunocompromise (steroids, HIV).
Surface Skirmishes - Skin & Nail Invaders
- Paronychia: Periungual tissue infection.
- Acute: S. aureus, Streptococci. Tx: Warm soaks, antibiotics. I&D (lift eponychial fold / incise with No. 11 blade).
- Chronic (>6 wks): Candida albicans, GNBs. Tx: Avoid irritants, antifungals/steroids. Marsupialization.

- Felon: Digital pulp infection (closed septal compartments).
- Clinical: Throbbing pain, tense swelling.
- Complications: Osteomyelitis, flexor tenosynovitis, necrosis.
- Tx: I&D. Incisions: Unilateral longitudinal, hockey-stick.
⭐ Transverse incisions for felon drainage are generally contraindicated due to risk of neurovascular injury or flexion contracture.
- Erysipeloid: Caused by Erysipelothrix rhusiopathiae.
- Source: Occupational: butchers, fish handlers.
- Clinical: Violaceous, demarcated lesion (fingers/hand).
- Tx: Penicillin.
Deeper Dangers - Tendons & Spaces
Flexor Tenosynovitis (FTS): Infection of flexor tendon sheath.
- 📌 Kanavel's Signs (FLEX):
- Finger held in slight Flexion
- Length of tendon sheath tender (palpation)
- Enlarged finger (fusiform/symmetrical swelling)
- Xtension (passive) of finger causes pain
- Pathogens: S. aureus (common), Strep.
- Tx: Urgent IV Abx & surgical drainage (Brunner/mid-axial incisions).
⭐ Kanavel's signs are pathognomonic for flexor tenosynovitis.

Deep Space Infections: Serious; require prompt drainage.
- Thenar Space:
- Signs: Thumb abducted, swollen & painful thenar eminence.
- Drainage: Dorsal (1st web) or volar (thenar crease) incision.
- Midpalmar Space:
- Signs: Loss of palmar concavity, dorsal swelling often present.
- Drainage: Transverse palmar or longitudinal dorsal incisions.
- Hypothenar Space:
- Signs: Swelling & tenderness over hypothenar eminence.
- Drainage: Ulnar border incision (mid-axial).
- Web Space (Collar-Button Abscess):
- Signs: "Dumbbell" swelling (dorsal & volar), abducted fingers.
- Drainage: Dorsal & volar longitudinal/zigzag incisions.
Special Ops - Unique Foes & Joints
- Herpetic Whitlow:
- Viral (HSV). Painful vesicles, digits. Pain out of proportion.
- Dx: Tzanck smear (multinucleated giant cells).
- Rx: Acyclovir. AVOID incision & drainage.
⭐ Herpetic whitlow should not be surgically incised; can worsen infection or cause secondary bacterial infection.
- Atypical Mycobacterial Infections (e.g., M. marinum):
- "Fish tank granuloma". Hx: aquatic exposure.
- Chronic, indolent course; papules, nodules, ulcers.
- Dx: Biopsy, culture (Löwenstein-Jensen at 30-32°C).
- Rx: Prolonged multi-drug therapy (e.g., clarithromycin + rifampicin/ethambutol).

- Septic Arthritis (Hand Joints):
- Causes: Direct inoculation, hematogenous.
- Dx: Joint aspiration (WBC >50,000/µL, Gram stain, culture).
- Rx: IV antibiotics, urgent surgical arthrotomy/washout.
- Bite Wounds:
- Human: Eikenella corrodens.
- Animal (cat/dog): Pasteurella multocida.
- Rx: Thorough debridement, irrigation, prophylactic antibiotics (e.g., amoxicillin-clavulanate).
High‑Yield Points - ⚡ Biggest Takeaways
- Kanavel's four cardinal signs are diagnostic for flexor tenosynovitis.
- Staphylococcus aureus is the most common causative organism in most hand infections.
- Paronychia involves the nail fold; felon affects the digital pulp.
- Herpetic whitlow is a viral infection (HSV); avoid incision and drainage.
- Human bites (fight bites) are high-risk for polymicrobial infections including Eikenella corrodens; require aggressive treatment.
- Deep space infections (e.g., thenar, midpalmar) necessitate prompt surgical drainage.
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