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Dysphonia Defined - Hoarse Whisperings

  • Dysphonia: Any abnormality in voice quality (e.g., hoarse, breathy, strained).
  • Larynx Anatomy Essentials:
    • Cartilages: Thyroid, cricoid, arytenoids (paired), epiglottis.
    • Intrinsic Muscles:
      • Thyroarytenoid (Vocalis): Body of vocal fold; shortens/relaxes (tensor/adductor).
      • Posterior Cricoarytenoid (PCA): Sole abductor. 📌 PCA: 'Party Cord Opener'.
      • Others: Lateral cricoarytenoid, interarytenoid (adductors); Cricothyroid (tensor, SLN).
    • Nerve Supply:
      • Recurrent Laryngeal Nerve (RLN): All intrinsic muscles except cricothyroid; sensory below vocal cords.
      • Superior Laryngeal Nerve (SLN): External branch (motor to cricothyroid); Internal branch (sensory above vocal cords).
  • Physiology of Phonation:
    • Myoelastic-Aerodynamic Theory: Vocal fold vibration results from a balance of muscle tension (myoelastic properties) and aerodynamic forces (Bernoulli effect of exhaled air).

Laryngeal cartilages, muscles, and vocal folds

⭐ The posterior cricoarytenoid (PCA) muscle is the sole abductor of the vocal cords, innervated by the recurrent laryngeal nerve (RLN).

Etiology Spectrum - Why So Hoarse?

  • Organic Causes:
    • Inflammatory: Acute/Chronic Laryngitis
    • Structural: Nodules, Polyps, Cysts, Reinke's, Granuloma, Sulcus, Web, Cancer
    • Traumatic: Intubation/External trauma
  • Functional Causes:
    • Muscle Tension Dysphonia (MTD)
    • Puberphonia
    • Psychogenic Dysphonia/Aphonia
  • Neurological Causes:
    • Vocal Cord Palsy (RLN/SLN)
    • Spasmodic Dysphonia
    • Parkinson's, Myasthenia
  • Systemic Causes:
    • Hypothyroidism
    • LPRD

Vocal cord lesions: nodules, polyp, and cyst

FeatureVocal NodulesVocal PolypsVocal Cysts
LocationBilateral, Ant 1/3-Post 2/3 jnct.Unilateral (usu.), mid-membranous foldUnilateral, in SLP
EtiologyChronic voice abuseAcute voice abuse/traumaMucous gland block/congenital
AppearanceSmall, white, callousLg, red/pale, gelatinous/hemorrhagicSubmucosal, yellow/white, rnd
Voice QualityBreathy, hoarse, effortfulHoarse, diplophonia, breathyHoarse, diplophonia (size-dep.)

Clinical Approach - Unmasking Dysphonia

History Taking:

  • Onset (sudden/gradual), duration (acute <3 weeks, chronic >3 weeks), progression.
  • Severity: GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain) 📌.
  • Associated: Odynophonia, dysphagia, stridor, cough, globus.
  • Vocal habits, occupation, smoking/alcohol. Hoarseness >3 weeks warrants laryngoscopy.

Red Flags for Malignancy:

Symptom/SignNote
Persistent HoarsenessEsp. smokers, >3 wks
Unexplained Weight LossSystemic sign
HemoptysisBleeding
Neck MassMetastasis
Referred OtalgiaNerve involvement
  • Voice: Quality, pitch, loudness.
  • Laryngeal Exam:
    • IDL.
    • FNPLS (gold standard).
    • Videostroboscopy (mucosal wave).
  • Neck Palpation.

Flexible Laryngoscopy and Vocal Cord Oscillation

⭐ Videostroboscopy is crucial for differentiating benign vocal fold lesions like cysts from nodules or polyps by assessing the mucosal wave, which is typically reduced or absent over a cyst.

Common Culprits - Vocal Villains

  • Acute Laryngitis: Viral. Hoarseness. Mgt: Voice rest, hydration.
  • Vocal Nodules: Voice abuse. Bilateral, 'singer's nodes'. Mgt: Voice therapy; surgery if refractory.
  • Vocal Polyps: Voice abuse/trauma. Unilateral. Mgt: Voice therapy, microlaryngeal surgery.
  • Reinke's Edema: Smoking, 'smoker's voice'. Bilateral diffuse swelling. Mgt: Smoking cessation, voice therapy, surgery.
  • Vocal Cord Paralysis: Iatrogenic (thyroidectomy), malignancy, idiopathic.
    • Unilateral: Breathy voice, aspiration risk.
    • Bilateral: Stridor, airway emergency.
    • Invx: CT. Mgt: Voice therapy, injection, thyroplasty.
  • Laryngeal Carcinoma: Risks: Smoking, alcohol. Persistent hoarseness. Early glottic: good prognosis.
FeatureAcute LaryngitisVocal NodulesVocal PolypsReinke's Edema
EtiologyViralVoice abuseVoice abuse/traumaSmoking
LateralityBilateralBilateralUnilateralBilateral
Key FeatureInflammation'Singer's nodes'Sessile/pedunc.'Smoker's voice'
Mgt (Prim.)Voice restVoice therapyVoice Rx/SurgeryStop smoking

⭐ The most common cause of iatrogenic unilateral vocal cord paralysis is thyroid surgery due to recurrent laryngeal nerve injury.

High‑Yield Points - ⚡ Biggest Takeaways

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