Surgical Complications - Setting the Stage
- Definition: Deviation from ideal post-op course.
- Timing:
- Immediate: <24 hrs (e.g., hemorrhage, anesthetic reaction).
- Early: 1-30 days (e.g., SSI, DVT, atelectasis).
- Late: >30 days (e.g., hernia, adhesions, pain).
- Severity Grading: Clavien-Dindo Classification (I-V).
- I: Minor deviation; no specific treatment.
- II: Pharmacological Rx (incl. transfusion, TPN).
- III: Surgical, endoscopic, or radiological intervention.
- IIIa: Intervention w/o GA.
- IIIb: Intervention w/ GA.
- IV: Life-threatening; ICU care.
- IVa: Single organ dysfunction.
- IVb: Multi-organ dysfunction.
- V: Death.
- Suffix 'd': Disability at discharge.
⭐ Clavien-Dindo Grade IIIb requires surgical, endoscopic, or radiological intervention, typically under general anesthesia.
Surgical Complications - Wound Woes
- Hematoma: Collection of blood.
- Risk: Inadequate hemostasis, anticoagulants.
- Mx: Small - observe; Large/expanding - evacuate.
- Seroma: Collection of serous fluid.
- Mx: Aspiration (sterile), pressure dressing; recurrent - sclerosant/drain.
- Surgical Site Infection (SSI): Infection at/near surgical incision within 30 days (or 1 year if implant).
- Types: Superficial, Deep incisional, Organ/space.
- Mx: Antibiotics, drainage, debridement.
⭐ Staphylococcus aureus is the most common pathogen in SSIs.
- Wound Dehiscence: Partial/complete separation of wound layers.
- Risk factors: ↑intra-abdominal pressure, poor nutrition, infection.
- Evisceration: Protrusion of viscera through dehisced wound (surgical emergency!).
- Mx: Sterile saline-soaked gauze, immediate OR.
- Fistula: Abnormal communication between two epithelial surfaces.
- Incisional Hernia: Protrusion of abdominal contents through previous incision site.

Surgical Complications - Systemic Storms
⭐ The "5 W's" (Wind, Water, Wound, Walking, Wonder drugs/What did we do?) is a classic mnemonic for causes of post-operative fever based on timing.
- Post-Op Fever (📌 5 W's):
- Wind (Atelectasis, Pneumonia): POD 1-3.
- Water (UTI): POD 3-5.
- Wound (Infection): POD 5-7.
- Walking (DVT/PE): POD 7+.
- Wonder Drugs (Drug fever): Anytime.
- Key Systemic Issues:
- Respiratory: Atelectasis (commonest early fever), Pneumonia, PE (DVT prophylaxis).
- Cardiovascular: DVT (Wells, Doppler), MI (peri-op stress).
- GI: Ileus (prolonged >3-5 days), Anastomotic leak (fever, ↑HR).
- GU: UTI (CAUTI), AKI (monitor UO).
- SIRS/Sepsis:
- SIRS: ≥2 (T >38°C/<36°C, HR >90, RR >20 or $P_aCO_2 < \textbf{32}$ mmHg, WBC >12k/<4k/>10% bands).
- Sepsis: SIRS + infection → MODS.

Surgical Complications - Critical Crises
- Shock: Acute circulatory failure.
- Hypovolemic: ↓Volume (hemorrhage). Treat: Fluids, blood, stop loss.
- Septic: Infection + dysregulated host response. Treat: Fluids, antibiotics, vasopressors.
- Cardiogenic: Pump failure (e.g., MI). Treat: Inotropes, address cause.
- Neurogenic: Sympathetic tone loss (spinal injury). Treat: Vasopressors, atropine.
- SIRS, Sepsis, Septic Shock:
- SIRS: ≥2: Temp >38°C/<36°C; HR >90/min; RR >20/min or PaCO₂ <32mmHg; WBC >12,000/mm³/<4,000/mm³ or >10% bands.
- Sepsis: SIRS + suspected/confirmed infection.
- Septic Shock: Sepsis + hypotension despite fluids, requiring vasopressors & lactate >2 mmol/L.
⭐ Key components of qSOFA score (≥2 points suggests higher risk of poor outcome with sepsis): Respiratory Rate ≥22/min, Altered Mentation (GCS <15), Systolic Blood Pressure ≤100 mmHg.

High‑Yield Points - ⚡ Biggest Takeaways
- Staphylococcus aureus is the most common cause of Surgical Site Infections (SSI).
- Post-op fever causes (5 W's): Atelectasis (Day 1-2), UTI (Day 3-5), SSI (Day 5-7), DVT/PE (Day 7+), Drug fever.
- Wound dehiscence is fascial separation; evisceration involves visceral protrusion.
- DVT prophylaxis is critical in major surgeries to prevent pulmonary embolism.
- Anastomotic leaks in GI surgery present with sepsis and require prompt management.
- Malignant hyperthermia, triggered by anesthetics, is treated with dantrolene.
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