Pre-op Assessment & Risk - Setting the Stage
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ASA Physical Status Classification:
Status Description ASA I Normal healthy patient ASA II Mild systemic disease ASA III Severe systemic disease ASA IV Severe systemic disease, constant threat to life ASA V Moribund, not expected to survive without operation ASA VI Declared brain-dead, organ donor E Emergency procedure -
Pre-anesthetic Evaluation:
- Focused Hx: Allergies, medications, prior anesthesia Hx, comorbidities.
- Airway Assessment (📌 LEMON mnemonic for difficult airway):
- Mallampati score.

- Thyromental distance (>6.5 cm).
- Inter-incisor gap (>3 cm).
- Neck mobility.
- Mallampati score.
⭐ NPO guidelines are crucial to prevent aspiration:
- Clear liquids: 2 hrs.
- Breast milk: 4 hrs.
- Light meal/Infant formula: 6 hrs.
- Fatty/fried meal: 8 hrs.
- Informed Consent: Essential for anesthesia plan and risks discussion.
Types of Anesthesia - Pick Your Potion
- General Anesthesia (GA): Reversible loss of consciousness.
- Phases: Induction, Maintenance, Emergence.
- Total Intravenous Anesthesia (TIVA): GA using IV agents only.
- Regional Anesthesia: Numbs a larger body area.
- Spinal: Injection into subarachnoid space (L3-L4/L4-L5). Agents: Bupivacaine. Baricity affects spread. Complications: Hypotension, Post-Dural Puncture Headache (PDPH).
- Epidural: Catheter in epidural space. Advantage: Prolonged post-op analgesia.
- Local Anesthesia (LA): Numbs a small, specific area.
- Mechanism: Blocks Na+ channels.
- Types: Amides (Lignocaine, Bupivacaine), Esters (Procaine).
- Max Doses: Lignocaine (plain 3-5 mg/kg; +adrenaline 7 mg/kg). Bupivacaine (plain 2-2.5 mg/kg).
- Toxicity: 📌 SAMS: Slurred speech, Altered mental status, Muscle twitching, Seizures.
- Monitored Anesthesia Care (MAC): Sedation with local anesthesia; patient responsive.
⭐ Spinal anesthesia commonly uses hyperbaric Bupivacaine; post-dural puncture headache (PDPH) is a known complication, often managed conservatively or with an epidural blood patch.
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Types of Anesthesia - Pick Your Potion
- General Anesthesia (GA): Reversible unconsciousness. Phases: Induction, Maintenance, Emergence. TIVA option.
- Regional Anesthesia:
- Spinal: Subarachnoid injection (L3-L5). Agent: Bupivacaine. Complications: Hypotension, PDPH.
- Epidural: Catheter for prolonged analgesia.
- Local Anesthesia (LA): Na+ channel blockade.
- Amides (Lignocaine, Bupivacaine), Esters (Procaine).
- Max Doses: Lignocaine (plain 3-5 mg/kg; +adrenaline 7 mg/kg). Bupivacaine (plain 2-2.5 mg/kg).
- Toxicity: 📌 SAMS (Slurred speech, Altered mental status, Muscle twitching, Seizures).
- Monitored Anesthesia Care (MAC): Sedation + LA.
⭐ Spinal: Hyperbaric Bupivacaine common. PDPH risk; manage conservatively or blood patch.
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Airway Management & Drugs - Breath & Beyond
- Basic Airway:
- Maneuvers: Head-tilt/chin-lift, jaw thrust.
- Devices: OPA, NPA (unconscious, no gag), LMA (supraglottic), ETT (definitive airway).
- RSI (Rapid Sequence Intubation): Full stomach/aspiration risk. Steps: Preoxygenate, cricoid pressure, induction, paralysis, intubate.
- IV Anesthetics:
- Propofol: SE: hypotension, apnea.
- Etomidate: CVS stable.
- Ketamine: Dissociative, bronchodilation, analgesia. SE: emergence delirium.
- Inhalational: Sevoflurane, Desflurane, Isoflurane (MAC = potency). N2O (second gas effect).
- Muscle Relaxants:
- Succinylcholine (Depolarizing): SE: hyperkalemia, fasciculations, MH trigger.
- Rocuronium, Vecuronium (Non-depolarizing): Reverse: Neostigmine/Glycopyrrolate or Sugammadex.
⭐ Malignant Hyperthermia: Rare; due to succinylcholine/inhalational agents. Treat: Dantrolene 2.5 mg/kg IV.
Intra-op Monitoring & Complications - Crisis Control
- Standard ASA Monitoring: ECG, NIBP, SpO2, EtCO2 (ETT, ventilation), Temp.
⭐ Capnography (EtCO2): Most reliable for ETT confirmation & ventilation adequacy.
- Common Complications:
- Hypotension: Causes (drugs, blood loss, sympathetic block). Mgmt: Fluids, vasopressors.
- Hypoxia: Causes (airway, breathing, circulation). Mgmt: 100% O2, ABCs.
- Anaphylaxis: Signs (↓BP, bronchospasm, rash). Mgmt: Adrenaline 0.3-0.5 mg IM/IV, fluids, steroids, antihistamines.
- Malignant Hyperthermia (MH):
- Triggers: Succinylcholine, volatile anesthetics.
- Signs: Early (↑EtCO2, tachycardia, rigidity); Late (hyperthermia, rhabdomyolysis).
- Mgmt: Stop triggers, 100% O2 hyperventilation, Dantrolene 2.5 mg/kg IV (repeat PRN), cooling, treat acidosis/hyperK+.
- Awareness under anesthesia: Rare; risk factors (paralysis, difficult intubation).
High‑Yield Points - ⚡ Biggest Takeaways
- ASA classification predicts perioperative risk.
- Mallampati score assesses airway; higher scores mean difficult intubation.
- Malignant hyperthermia (MH), triggered by succinylcholine/volatiles, is treated with dantrolene.
- Propofol is a common IV anesthetic; ketamine provides analgesia and cardiovascular stability.
- Spinal anesthesia: local anesthetic into subarachnoid space for rapid onset.
- Local Anesthetic Systemic Toxicity (LAST): manage with IV lipid emulsion.
- Rapid Sequence Intubation (RSI) for full stomach patients prevents aspiration_._
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