Pregnant Patient Physiology & Risks - Code Red Mama
- Cardiovascular: ↑CO (30-50%), ↑HR. Supine hypotension (aortocaval compression) - LUD crucial.
- Respiratory: ↑O₂ demand, ↑MV, ↓FRC (20-30%) → rapid desaturation. Airway edema → difficult intubation risk.
- Gastrointestinal: ↓LES tone, delayed gastric emptying → ↑aspiration risk.
- Nervous System: ↓MAC (up to 30%). ↓Epidural/spinal volume.
- Key Risks:
- Difficult airway
- Aspiration (Mendelson's)
- Rapid O₂ desaturation
- Supine hypotension
- ↑Drug sensitivity 📌 "HERO" for High-Risk Obstetric Patient: Hypotension (supine), Emptying (gastric delayed), Respiratory (↓FRC, edema), Oxygen (desaturation fast).
⭐ Aortocaval compression by the gravid uterus causes supine hypotension. Prevent with left uterine displacement (LUD) of at least 15°.

Airway & RSI in Obstetrics - Can't Breathe, Baby!
- Airway Challenges:
- ↑ Airway edema, friability (bleeding risk).
- ↓ FRC, ↑ O2 consumption → rapid desaturation.
- Mallampati score often ↑.
- RSI (Assume Full Stomach):
- Pre-oxygenation: 3-5 min 100% O2 or 4-8 vital capacity breaths.
- Cricoid pressure (Sellick’s).
- Drugs:
- Induction: Propofol (1.5-2.5 mg/kg), Ketamine (1-2 mg/kg).
- Paralysis: Succinylcholine (1-1.5 mg/kg).
- ETT size: 6.0-7.0 mm.
- Difficult Airway Plan:
- Anticipate (LEMON).
- SADs, AFOI, surgical airway ready.
⭐ Due to ↓FRC and ↑O2 consumption, pregnant patients desaturate very rapidly (within 2-3 min) after apnea.

Anesthesia for Emergency C-Section - Speedy Delivery Anesthesia
- Goal: Rapid, safe anesthesia for mother & fetus.
- Choice: General Anesthesia (GA) vs. Regional (Spinal).
- GA Indications:
- Extreme urgency (e.g., fetal distress, hemorrhage).
- Regional contraindicated/failed.
- Maternal refusal.
- Spinal Anesthesia: Preferred if time permits (>10-15 min to incision) & no contraindications. Faster onset than epidural.
- GA Technique (RSI - Rapid Sequence Intubation):
- Preoxygenation: 100% O2 for 3-5 min.
- Induction: Propofol or Ketamine (if hemodynamically unstable).
- Muscle Relaxant: Succinylcholine or Rocuronium.
- Maintain: Volatiles (0.5-0.75 MAC till delivery), then ↑.
- Aspiration Prophylaxis: Crucial (e.g., Ranitidine, Sodium Citrate).
- Left Uterine Displacement (LUD): Essential.
⭐ Maintain left uterine displacement (LUD) of at least 15 degrees or manual displacement until delivery to prevent aortocaval compression.
Managing Obstetric Crises - Mayday! Mayday! Mama Needs Help!
- General Approach:
- Key Crises & Anesthetic Pointers:
- Amniotic Fluid Embolism (AFE): Sudden CV collapse, hypoxia, coagulopathy. Rx: Aggressive supportive care (ABC, O2, intubation, vasopressors, blood products), ICU. 📌 A-OK (Atropine, Ondansetron, Ketorolac) - controversial.
- Major Obstetric Hemorrhage (MOH):
- Causes: 4Ts (Tone, Trauma, Tissue, Thrombin). Atony common.
- Rx: Call for help (MTP!), ABCs. Uterotonics (Oxytocin etc.), surgical control. GA.
⭐ Activate Massive Transfusion Protocol (MTP) early: PRBC:FFP:Platelets in 1:1:1 ratio.
- Eclampsia: Seizures + preeclampsia. Rx: Magnesium sulfate (4-6g IV load, 1-2g/hr). Airway, O2. Avoid Ketamine.
- Uterine Rupture: Fetal distress, maternal shock. Rx: Emergency laparotomy. RSI + GA. Aggressive resuscitation.
- Placental Abruption: Painful bleed, fetal distress. Rx: Emergency CS. GA. Prepare for DIC.

High‑Yield Points - ⚡ Biggest Takeaways
- Aspiration prophylaxis (e.g., ranitidine, sodium citrate) is crucial before any anesthetic.
- Higher risk of difficult airway in parturients; always be prepared.
- Rapid Sequence Intubation (RSI) is the technique of choice for General Anesthesia (GA).
- Maintain left uterine displacement continuously to prevent aortocaval compression.
- Proactively manage maternal hypotension following neuraxial or general anesthesia.
- Anticipate and manage Postpartum Hemorrhage (PPH) with uterotonics.
- GA is preferred for Category 1 (most urgent) C-sections due to speed of onset.
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