Central Vertigo

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Central Vertigo Basics - Brain's Dizzy Dance

  • Pathophysiology: Dysfunction of central vestibular pathways.
  • Onset: Often gradual; can be sudden (e.g., stroke, hemorrhage).
  • Vertigo Character:
    • Less intense, more ill-defined than peripheral.
    • Often constant, may feel like imbalance.
  • Nystagmus:
    • Pure vertical, torsional, or horizontal.
    • May change direction with gaze.
    • Not suppressed by visual fixation.
  • Associated Features: Neurological deficits common (diplopia, dysarthria, ataxia).
  • Hearing Loss/Tinnitus: Typically absent.
  • Autonomic Symptoms (nausea/vomiting): Less severe.

⭐ Central vertigo originates from lesions within the brainstem or cerebellum.

Etiology Unmasked - Central Culprit Hunt

  • Vascular (Most Common):
    • Brainstem Ischemia/Infarction (e.g., pons, medulla)
    • Cerebellar Ischemia/Infarction/Hemorrhage
    • Vertebrobasilar Insufficiency (VBI): Transient symptoms
    • Wallenberg Syndrome (Lateral Medullary Syndrome - PICA occlusion)
    • Subclavian Steal Syndrome
  • Demyelinating Disease:
    • Multiple Sclerosis (MS): Plaques in brainstem or cerebellar pathways
  • Neoplastic:
    • Posterior Fossa Tumors:
      • Cerebellar (e.g., medulloblastoma, astrocytoma, hemangioblastoma)
      • Brainstem (e.g., glioma)
      • Metastases
  • Migraine:
    • Vestibular Migraine: Episodic vertigo with migrainous features
  • Infectious/Inflammatory:
    • Brainstem Encephalitis (e.g., viral, Listeria)
    • Cerebellitis
    • Tuberculoma, Neurocysticercosis (NCC) in posterior fossa
  • Traumatic Brain Injury (TBI):
    • Brainstem or cerebellar contusions/hematomas
  • Degenerative Disorders:
    • Spinocerebellar Ataxias (SCAs)
    • Paraneoplastic Cerebellar Degeneration
  • Medication/Toxin-Induced (Rarely isolated central):
    • Anticonvulsants (e.g., phenytoin), alcohol, chemotherapy agents

⭐ Vertebrobasilar insufficiency is a common vascular cause of central vertigo, especially in elderly patients.

Symptoms & Signs - Decoding Dizziness Clues

  • Vertigo Characteristics: Often persistent, may be less intense than peripheral but continuous; not always position-dependent.
  • Nystagmus (Key Central Features):
    • Purely vertical (upbeating/downbeating) or purely torsional.
    • Direction-changing gaze-evoked nystagmus (changes direction with gaze).
    • Often not suppressed by visual fixation.
  • Associated Neurological Deficits (The "5 Ds + A"):
    • Diplopia, Dysarthria, Dysphagia, Dysmetria (ataxia, incoordination), motor/sensory Deficits.
    • Altered consciousness (less common, but ominous).
  • Hearing Loss/Tinnitus: Typically ABSENT (key differentiator from many peripheral causes).
  • Gait: Severe ataxia, often unable to stand or walk unassisted, even with eyes open.
  • 📌 HINTS Exam (Head Impulse, Nystagmus, Test of Skew): Crucial for differentiating central (e.g., stroke) from peripheral causes in acute vestibular syndrome.
    • Head Impulse: Normal (Vestibulo-Ocular Reflex intact) often points to central.
    • Nystagmus: Central type (see above).
    • Test of Skew: Skew deviation present suggests central.
    • (Recall 📌 INFARCT: Impulse Normal, Fast-phase Alternating nystagmus, Refixation on Cover Test)

⭐ Purely vertical or purely torsional nystagmus, or direction-changing gaze-evoked nystagmus, strongly suggests a central cause.

Diagnosis & Care - Navigating Neuro-Vertigo

  • Clinical Evaluation:
    • History: Focus on 📌 "4 Ds" (Dizziness, Diplopia, Dysarthria, Dysphagia), headache, weakness.
    • Neuro Exam: Cranial nerves, cerebellar signs (ataxia, dysmetria); nystagmus (vertical, pure torsional, direction-changing, non-fatigable).
  • Investigations:
    • MRI Brain (with DWI): Essential for posterior fossa pathology.
    • CT Brain: Acute setting if MRI delayed/contraindicated.
    • Audiometry: Usually normal. VNG may show central patterns.
  • Management Strategy:
    • Treat Etiology: Ischemia (stroke care), tumor (surgery/RT), MS (DMTs).
    • Symptomatic Relief: Antiemetics (e.g., ondansetron), limited vestibular suppressants (e.g., diazepam).
    • Vestibular Rehabilitation (VRT): For chronic imbalance.
    • Specialist Referral: Neurologist.

⭐ MRI of the brain is the gold standard investigation for suspected central vertigo to identify structural lesions.

High‑Yield Points - ⚡ Biggest Takeaways

  • Central vertigo originates from brainstem or cerebellar pathology.
  • Nystagmus is typically vertical, bidirectional, or purely torsional, and not suppressed by visual fixation.
  • Hearing loss and tinnitus are generally absent; if present, suspect other causes.
  • Prominent neurological signs (e.g., ataxia, dysarthria, diplopia, weakness) are key differentiators.
  • Vertigo is often milder but more constant and disabling than peripheral types.
  • Key causes include posterior circulation stroke/TIA, multiple sclerosis, cerebellar tumors, and vestibular migraine.

Practice Questions: Central Vertigo

Test your understanding with these related questions

A 47-year-old man presents to the emergency room with symptoms of dizziness and difficulty walking. He describes his dizziness as a spinning sensation of the room with associated nausea and vomiting. Which of the following findings suggests the vertigo is peripheral in origin?

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Flashcards: Central Vertigo

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What is the classical triad of Meniere's disease?_____

TAP TO REVEAL ANSWER

What is the classical triad of Meniere's disease?_____

Episodic vertigo, fluctuating hearing loss and tinnitus

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