Deep Neck Space Infections

Deep Neck Space Infections

Deep Neck Space Infections

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Anatomy - Neck's Hidden Hubs

  • Cervical Fascia:
    • Superficial: Encloses platysma.
    • Deep:
      • Investing: Surrounds SCM, trapezius.
      • Pretracheal: Forms visceral compartment.
      • Prevertebral: Covers vertebral column/muscles.
  • Key Deep Neck Spaces:
    • Parapharyngeal (Lateral Pharyngeal): Lateral to pharynx.
    • Retropharyngeal: Post. to pharynx; btw buccopharyngeal & alar fascia.
    • Danger Space: Between alar & prevertebral fascia.

      ⭐ Extends skull base to diaphragm; "Highway for infection".

    • Prevertebral: Ant. to vertebrae, deep to prevertebral fascia.
    • Submandibular: Sublingual & submaxillary areas.
    • Carotid Sheath: Common/internal carotid a., IJV, CN X.
    • Pretracheal (Visceral): Surrounds trachea, esophagus, thyroid. Axial neck anatomy showing deep spaces and fasciaoka

Etiology & Bugs - Infection Invasion

  • Etiology (Sources):
    • Odontogenic (most common; mandibular molars)
    • Tonsillopharyngeal (e.g., peritonsillar abscess)
    • Salivary gland (sialadenitis)
    • Trauma, IV drug use
  • Common Pathogens (Often Polymicrobial):
    • Aerobes: Streptococcus spp. (viridans, pyogenes), Staphylococcus aureus
    • Anaerobes: Peptostreptococcus, Bacteroides, Prevotella, Fusobacterium
  • Invasion: Direct spread, lymphatic.

Fusobacterium necrophorum is classically associated with Lemierre's syndrome (postanginal sepsis, IJV thrombophlebitis).

Clinical Clues & Dx - Spotting the Sepsis

  • General: Fever, neck pain/swelling, dysphagia, odynophagia, trismus.
  • Airway: Stridor, dyspnea - ⚠️ EMERGENCY!
  • Specific Signs: Vary by space (e.g., Ludwig's: woody submandibular swelling).
  • Investigation:
    • CT with contrast: GOLD STANDARD. Defines extent, abscess.
    • Labs: ↑WBC, ↑CRP.

Axial CT and MRI of deep neck abscess

⭐ Ludwig's angina (bilateral submandibular, sublingual, submental space infection) can cause rapid airway obstruction.

Key Infections - Danger Deep Dive

  • Ludwig's Angina:
    • Bilateral cellulitis: submandibular, sublingual, submental spaces.
    • Source: Odontogenic (mandibular molars).
    • Symptoms: "Woody" floor of mouth, tongue elevation, drooling, airway risk.
  • Retropharyngeal Abscess (RPA):
    • Children (<5 yrs): Often after URI; midline swelling, fever, torticollis, dysphagia.
    • Adults: Trauma, foreign body; can be lateral.
    • Risk: Danger space spread → mediastinitis.
  • Parapharyngeal Abscess (PPA):
    • Source: Tonsillar, pharyngeal, dental.
    • Symptoms: Trismus, medial pharyngeal wall bulge, fever, neck pain/swelling.
    • Compartments: Prestyloid (trismus prominent) vs. Poststyloid (cranial nerve palsies, vascular risk).

Sagittal view of deep neck spaces

⭐ In children, retropharyngeal abscesses are typically midline due to infection of retropharyngeal lymph nodes (nodes of Rouviere), which atrophy by age 4-5 years old.

Management & Mayhem - Treatment & Threats

  • Airway First! Secure immediately if compromised (stridor, dyspnea). Options: intubation, tracheostomy.

  • IV Antibiotics: Empiric broad-spectrum (e.g., Ampicillin-Sulbactam, Clindamycin +/- Metronidazole). Tailor to culture results.

  • Surgical Drainage Indications:

    • Airway compromise despite medical Rx
    • Definitive collection > 2-3 cm on CT scan
    • No clinical improvement in 24-48 hrs of IV antibiotics
    • Presence of complications (e.g., mediastinitis)
    • Specific spaces (e.g., Ludwig's angina often needs early drainage)
  • Dreaded Complications (Mayhem):

    • Airway Obstruction (esp. Ludwig's Angina)
    • Descending Necrotizing Mediastinitis (DNM) - high mortality
    • Sepsis / Septic Shock
    • Lemierre’s Syndrome (IJV thrombophlebitis, often F. necrophorum)
    • Carotid artery rupture, cranial nerve (CN) palsies

⭐ Ludwig's angina involves bilateral submandibular, sublingual, and submental spaces, rapidly progressing to airway obstruction if not managed promptly; it's a surgical emergency if airway is threatened or significant cellulitis/collection exists despite antibiotics.

  • Ludwig's angina: bilateral infection of submandibular, sublingual, submental spaces; odontogenic origin; high airway risk.
  • Parapharyngeal space infection: presents with trismus, medial bulge of lateral pharyngeal wall.
  • Retropharyngeal abscess: common in children <5 yrs; risk of mediastinitis, airway obstruction.
  • Danger space (Space 4): infection rapidly spreads to posterior mediastinum.
  • CT scan with contrast is key for diagnosis and extent.
  • Core management: Secure airway, IV antibiotics, prompt surgical drainage.
  • Predominant organisms: Aerobic Streptococci and anaerobes.

Practice Questions: Deep Neck Space Infections

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Most common cause of retropharyngeal abscess in adults?

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Flashcards: Deep Neck Space Infections

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_____ incision is used to access the floor of the maxillary sinus in the case of maxillary carcinoma.

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_____ incision is used to access the floor of the maxillary sinus in the case of maxillary carcinoma.

WeberFerguson

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