Neurobiological basis of depression — Flashcards

Flashcard 1: Depression is associated with _____ total REM sleep

Answer: increased

Flashcard 2: MAO inhibitors may be used to treat anxiety and treatment-resistant _____ depression (not first line)

Answer: atypical

Flashcard 3: Neuro/Psych Adverse effects of tricyclic antidepressants (TCAs) include respiratory _____ and hyperpyrexia

Answer: depression

Flashcard 4: Atypical depression is associated with _____, which is being able to experience improved mood in response to positive events, albeit briefly

Answer: mood reactivity

Flashcard 5: Atypical depression is associated with _____-phagia

Answer: hyper

Flashcard 6: depression

Answer:

Extra: early morning awakening incompletedecreased: NE, dopamine, serotonin

Flashcard 7: serotonin

Answer: raphe nucleus

Flashcard 8: A woman status post mastectomy says she feels ugly when she undresses.

Answer: Find out why the patient feels that way. Do not offer false reassurance or anything that could be interpreted as flirtation. (e.g. You still look great!)

Flashcard 9: What changes in sleep patterns are often seen in depressed patients?

Answer: 1. less delta-wave sleep 2. more REM sleep 3. more/earlier awakenings (decreased delta-wave sleep (stage N3) decreased REM latency increased REM early in sleep cycle increased total time in REM repeated nighttime awakenings early-morning awakening)

Flashcard 10: Major depressive disorder with seasonal pattern is most associated with what season? _____

Answer: Winter

Extra:  https://onlinemeded.org/spa/psychiatry/mood-disorders/acquire?ref=anki