Calcium and phosphate handling — Flashcards

Flashcard 1: PTH increases phosphate _____ by the kidney.

Answer: excretion

Flashcard 2: How does renal insufficiency cause secondary hyperparathyroidism? (sorry) _____

Answer: 1. Renal insufficiency causes decreased phosphate excretion and thus increased serum phosphate levels 2. Increased serum phosphate may bind free, ionized calcium, thus decreasing serum calcium levels 3. Decreased free calcium stimulates PTH release from the parathyroid glands

Flashcard 3: Thiazide diuretics increase Ca2+ _____ (excretion or reabsorption)

Answer: reabsorption

Flashcard 4: In chronic renal failure, increased serum phosphate complexes Ca2+ and leads to decreased _____

Answer: free, ionized Ca2+

Flashcard 5: With regards to renal physiology, what does [TF] stand for? _____

Answer: Concentration in tubular fluid

Flashcard 6: The major regulatory mechanism of the proximal tubule is _____

Answer: glomerulotubular balance

Flashcard 7: In the _____ of the nephron, Ca2+ is reabsorbed by an apical Ca2+ channel and a basolateral Na+-Ca2+ exchanger

Answer: DCT

Flashcard 8: The [TF/P]glucose and [TF/P]AA ratios _____ over the course of the PCT

Answer: decrease

Extra:   https://onlinemeded.org/spa/renal?ref=anki 

Flashcard 9: The corticopapillary osmotic gradient is established, in part, by _____ multiplication

Answer: countercurrent

Extra:  https://onlinemeded.org/spa/nephrology?ref=anki 

Flashcard 10: The Na+ reabsorption mechanism of the thick ascending limb is _____-dependent (increased Na+ delivery causes increased reabsorption)

Answer: load

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/nephron-transporters?index=4] https://onlinemeded.org/spa/renal?ref=anki