Aldosterone synthesis and release — Flashcards

Flashcard 1: At high concentrations, cortisol can bind to _____ receptors

Answer: mineralocorticoid (aldosterone)

Flashcard 2: Aldosterone leads to _____ epithelial Na+ channel (ENaC) activity

Answer: increased

Flashcard 3: The renin-angiotensin II-aldosterone system is activated in response to a _____ in mean arterial pressure

Answer: decrease

Flashcard 4: Aldosterone _____ the number of luminal membrane K+ channels in the late distal tubule and collecting duct

Answer: increases

Flashcard 5: The site of synthesis, storage, and release of renin is the _____ of the kidney

Answer: juxtaglomerular apparatus

Flashcard 6: How does hyperkalemia influence aldosterone secretion?_____

Answer: Increased aldosterone secretion

Flashcard 7: _____ secretion (from the zona glomerulosa) is under tonic, but not exclusive, control by ACTH

Answer: Aldosterone

Flashcard 8: Which hormones (2) are released in response to increased volume, and thus act as a "check" on the renin-angiotensin-aldosterone system? _____

Answer: ANP, BNP

Flashcard 9: How do blood sugar levels change in secondary adrenocortical deficiency? _____

Answer: Decreased (hypoglycemia)

Extra:   Watch Adrenal Insufficiency [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-adrenal-disorders-adrenal-insufficiency?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/endocrinology/adrenals/acquire?ref=anki 

Flashcard 10: How does hyperkalemia influence aldosterone secretion? _____

Answer: Increased aldosterone secretion

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/renin-angiotensin-aldosterone-system?index=2] https://onlinemeded.org/spa/nephrology?ref=anki