Endothelial function and dysfunction — Flashcards

Flashcard 1: Heart failure, hypotension, and shock may be caused by _____calcemia

Answer: hypo

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Flashcard 2: NO is produced in _____ cells, then diffuses into smooth muscle cells leading to relaxation.

Answer: endothelial

Flashcard 3: What is the first step of leukocyte extravasation? _____

Answer: Margination

Flashcard 4: Endothelial cells prevent thrombosis by secreting _____, which converts plasminogen to plasmin

Answer: tissue plasminogen activator (tPA)

Flashcard 5: What step of leukocyte extravasation occurs directly after margination?_____

Answer: Rolling

Flashcard 6: What is the clinical significance of watershed zones in cerebral circulation?

Answer: areas at the border of two artery distributions are prone to hypoxia and infarction during severe hypotension

Flashcard 7: Which basal ganglia pathway inhibits movement?

Answer: indirect mnemonic: indirect inhibits

Flashcard 8: What is the phrase used to describe action potential conduction in myelinated nerves?

Answer: saltatory conduction i.e. AP basically jumps from node to node

Flashcard 9: What is the function of myelin?

Answer: increases neuronal conduction velocity

Flashcard 10: Give the stages of mitosis.

Answer: prophase, metaphase, anaphase, telophase mnemonic: PMAT