What pharmokinetic term describes the theoretical volume occupied by total amount of drug in the body relative to its plasma concentration? _____
#2
To calculate bioavailability using graphs of plasma concentration vs time utilizing nonintravenous vs intravenous administration, what is the formula?_____
#3
What formula is used to calculate half-life in first-order elimination kinetics? _____
#4
In _____ order kinetics, the rate of reaction is directly proportional to the substrate (drug) concentration
#5
Which drug elimination is characterized by a constant amount of drug eliminated per unit time?_____
Half-life and steady state concepts US Medical PG Flashcards - Medical Study Cards
Master Half-life and steady state concepts with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Half-life and steady state concepts Flashcard Deck - 5 Cards
Flashcard 1: What pharmokinetic term describes the theoretical volume occupied by total amount of drug in the body relative to its plasma concentration? _____
Answer: Volume of distribution (Vd)
Flashcard 2: To calculate bioavailability using graphs of plasma concentration vs time utilizing nonintravenous vs intravenous administration, what is the formula?_____
Answer: F = (AUC oral x dose IV) / (AUC IV x dose oral)
Flashcard 3: What formula is used to calculate half-life in first-order elimination kinetics? _____
Answer:
Flashcard 4: In _____ order kinetics, the rate of reaction is directly proportional to the substrate (drug) concentration
Answer: first
Flashcard 5: Which drug elimination is characterized by a constant amount of drug eliminated per unit time?_____
Answer: Zero-order elimination
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