Which one of the following drugs is a cytochrome p450 inducer?_____
#2
Which drug elimination is characterized by a constant fraction of drug eliminated per unit time?_____
#3
Benzodiazepines are metabolized by the _____
#4
Phase _____ drug metabolism usually yields slightly polar, water-soluble metabolites (often still active)
#5
What phase of drug metabolism includes reduction, oxidation, and hydrolysis? _____
#6
Rectal and sublingual administration have such high bioavailability because drugs will _____
#7
Acute alcohol use leads to _____ of CYP-450
First-pass metabolism US Medical PG Flashcards - Medical Study Cards
Master First-pass metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
First-pass metabolism Flashcard Deck - 7 Cards
Flashcard 1: Which one of the following drugs is a cytochrome p450 inducer?_____
Answer: Rifampin
Flashcard 2: Which drug elimination is characterized by a constant fraction of drug eliminated per unit time?_____
Answer: First-order elimination
Flashcard 3: Benzodiazepines are metabolized by the _____
Answer: liver
Flashcard 4: Phase _____ drug metabolism usually yields slightly polar, water-soluble metabolites (often still active)
Answer: I
Flashcard 5: What phase of drug metabolism includes reduction, oxidation, and hydrolysis? _____
Answer: Phase I
Flashcard 6: Rectal and sublingual administration have such high bioavailability because drugs will _____
Answer: bypass portal circulation*
Flashcard 7: Acute alcohol use leads to _____ of CYP-450
Answer: inhibition
Keywords: First-pass metabolism flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
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