Antimetabolites (azathioprine, mycophenolate) — Flashcards

What enzyme is blocked by the immunosuppressant mycophenolate mofetil?_____

Azathioprine/6-MP use can result in increased risk for _____ due to immunosuppression

Azathioprine and 6-mercaptopurine are metabolized by _____ (enzyme)

Which phase of the cell cycle does azathioprine act at?_____

Which enzyme is inhibited by azathioprine/6-mercaptopurine?_____

Mycophenolate mofetil is used prophylactically to reduce _____

Which chemotherapeutic drug is associated with pancreatitis?_____

Azathioprine/6-MP have an _____ effect, hence why they are useful in the treatment of graft rejection, SLE, autoimmune hemolytic anemia, etc.