Gonadal hormones (estrogens, progestins) US Medical PG Flashcards - Medical Study Cards
Master Gonadal hormones (estrogens, progestins) with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Gonadal hormones (estrogens, progestins) Flashcard Deck - 10 Cards
Flashcard 1: What is the mechanism by which progestins, alone, act as a contraceptive? _____
Answer: Thicken cervical mucus
Flashcard 2: Estrogen analogs induce a _____-coaguable state
Answer: hyper
Flashcard 3: Oral _____ contain high doses of estrogen and progesterone (or progesterone alone) which prevent ovulation via inhibition of FSH and LH
Answer: contraceptives
Flashcard 4: Tamoxifen increases the risk of thromboembolic events and _____ cancer
Answer: endometrial
Flashcard 5: What is the effect of oral contraceptives on coagulability? _____
Answer: Increases coaguability
Flashcard 6: What drug class do mifeprostone and ulipristal belong to?_____
Answer: Anti-progestins
Flashcard 7: What drug class do anastrozole and letrozole belong to?_____
Answer: Aromatase inhibitors
Flashcard 8: mestranol
Answer: estrogen
Extra: hypognadism, ovarian failure, menstrual abnormalities, HRT in postmenopausal women, androgen-dependent prostate cancerestrogen receptor-positive breast cancer, hx DVTbinds estrogen receptorincreased risk of endometrial cancer, vaginal bleeding in postmenopausal women
Flashcard 9: clompihene
Answer: SERM
Extra: infertility and PCOSpartial agonist at estrogen receptor, prevents feedback inhibitionhot flashes, ovarian enlargement, multiple pregnancy, visual disturbances
Flashcard 10: tamoxifen
Answer: SERM
Extra: ER-positive breast cancerantagonist at estrogen receptor; specific for breast tissue
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