Bone metabolism drugs (bisphosphonates, RANKL inhibitors) US Medical PG Flashcards - Medical Study Cards
Master Bone metabolism drugs (bisphosphonates, RANKL inhibitors) with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Bone metabolism drugs (bisphosphonates, RANKL inhibitors) Flashcard Deck - 10 Cards
Flashcard 1: Metformin causes increased insulin _____, therefore enhancing glucose uptake in peripheral tissues
Answer: sensitivity
Flashcard 2: Teriparatide decreases _____ in patients with osteoporosis.
Answer: fractures
Flashcard 3: Thiazolidinediones can increase the risk of atypical extremity _____
Answer: fractures
Flashcard 4: As a result of decreased osteoclast activity, bisphosphonates may cause hypo-_____
Answer: calcemia
Flashcard 5: Raloxifene is primarily used to treat and prevent post-menopausal _____
Answer: osteoporosis
Flashcard 6: Bisphosphonates decrease the development and recruitment of _____ precursors
Answer: osteoclast
Flashcard 7: mestranol
Answer: estrogen
Extra: hypognadism, ovarian failure, menstrual abnormalities, HRT in postmenopausal women, androgen-dependent prostate cancer estrogen receptor-positive breast cancer, hx DVT binds estrogen receptor increased risk of endometrial cancer, vaginal bleeding in postmenopausal women
Flashcard 8: clompihene
Answer: SERM
Extra: infertility and PCOS partial agonist at estrogen receptor, prevents feedback inhibition hot flashes, ovarian enlargement, multiple pregnancy, visual disturbances
Flashcard 9: tamoxifen
Answer: SERM
Extra: ER-positive breast cancer antagonist at estrogen receptor; specific for breast tissue
Flashcard 10: raloxifene
Answer: SERM
Extra: osteoporosis (reduces bone resorption) agonist at estrogen receptor; specific to bone
Keywords: Bone metabolism drugs (bisphosphonates, RANKL inhibitors) flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
