Androgens and anabolic steroids US Medical PG Flashcards - Medical Study Cards
Master Androgens and anabolic steroids with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Androgens and anabolic steroids Flashcard Deck - 10 Cards
Flashcard 1: Ketoconazole has anti-androgenic effects and thus can cause _____ in males
Answer: gynecomastia
Flashcard 2: What is the mechanism of action of finasteride?_____
Answer: 5-reductase inhibitor
Flashcard 3: Dexamethasone, hydrocortisone, and prednisone are all examples of _____
Answer: glucocorticoids
Flashcard 4: Exogenous testosterone causes _____ hematocrit
Answer: increased
Flashcard 5: What adverse anti-androgenic effect may be caused by spironolactone use in males? _____
Answer: Gynecomastia
Flashcard 6: Spironolactone may have anti-androgenic effects via direct antagonism of the _____ receptor
Answer: androgen
Flashcard 7: mestranol
Answer: estrogen
Extra: hypognadism, ovarian failure, menstrual abnormalities, HRT in postmenopausal women, androgen-dependent prostate cancer estrogen receptor-positive breast cancer, hx DVT binds estrogen receptor increased risk of endometrial cancer, vaginal bleeding in postmenopausal women
Flashcard 8: clompihene
Answer: SERM
Extra: infertility and PCOS partial agonist at estrogen receptor, prevents feedback inhibition hot flashes, ovarian enlargement, multiple pregnancy, visual disturbances
Flashcard 9: tamoxifen
Answer: SERM
Extra: ER-positive breast cancer antagonist at estrogen receptor; specific for breast tissue
Flashcard 10: raloxifene
Answer: SERM
Extra: osteoporosis (reduces bone resorption) agonist at estrogen receptor; specific to bone
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