Pharmacovigilance principles — Flashcards

Phase _____ of clinical trials confirms efficacy compared to the standard of care, as well as adverse effects

Most loop diuretics are _____ drugs and thus may cause adverse reactions in allergic patients

Phase _____ of clinical trials is the postmarketing surveillance of patients after a treatment is approved

The _____-opioid receptor mediates most of the clinical and adverse effects

Examples of the beers criteria include drugs that increase the risk of anti_____ activity (antihistamines, GI antispasmodics)

What type of drug interaction is an acute decrease in response to a drug after initial/repeated administration?_____

Sulfonylureas are _____ drugs and thus may cause adverse reactions in allergic patients

First Aid Pharmacology: Autonomics ( blockers) -blockers may have _____ adverse effects, including seizures, sedation, and sleep alterations

thalidomide

warfarin