Pharmacodynamic interaction mechanisms US Medical PG Flashcards - Medical Study Cards
Master Pharmacodynamic interaction mechanisms with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Pharmacodynamic interaction mechanisms Flashcard Deck - 10 Cards
Flashcard 1: Buprenorphine, and butorphanol are -opioid _____
Answer: partial agonists
Flashcard 2: What type of drug interaction is the presence of A is required for the full effects of substance B?_____
Answer: Permissive (e.g. cortisol on catecholamine responsiveness)
Flashcard 3: Ondansetron may cause _____, which presents with symptoms including rigidity, tremor, hyperthermia, and confusion
Answer: serotonin syndrome
Flashcard 4: Warfarin is _____ by cytochrome P450 and thus has many drug interactions
Answer: metabolized
Flashcard 5: What type of drug interaction is the effect of substance A and B together is greater than the sum of their individual products?_____
Answer: Synergistic (e.g. clopidogrel with aspirin)
Flashcard 6: What type of drug interaction is an acute decrease in response to a drug after initial/repeated administration?_____
Answer: Tachyphylactic (e.g. nitrates, niacin, phenylephrine, LSD, MDMA)
Flashcard 7: What drug class do vardenafil, tadalafil, and sildenafil belong to?_____
Answer: PDE-5 inhibitors
Flashcard 8: Dextromethorphan may cause _____ if combined with other serotonergic agents
Answer: serotonin syndrome
Flashcard 9: thalidomide
Answer: limb defects (flipper limbs)
Flashcard 10: warfarin
Answer: bone deformities, fetal hemmorhage, abortion, ophthalmologic abnormalities
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