P-glycoprotein interactions US Medical PG Flashcards - Medical Study Cards
Master P-glycoprotein interactions with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
P-glycoprotein interactions Flashcard Deck - 9 Cards
Flashcard 1: Rifampin is given with Dapsone because it _____ to Dapsone
Answer: delays resistance
Flashcard 2: P-glycoprotein is encoded for by the _____
Answer: MDR1 gene
Flashcard 3: Azoles _____ cytochrome p450
Answer: inhibit
Flashcard 4: Aminoglycosides are actively transported into the cell via an _____-dependent process
Answer: oxygen
Flashcard 5: thalidomide
Answer: limb defects (flipper limbs)
Flashcard 6: warfarin
Answer: bone deformities, fetal hemmorhage, abortion, ophthalmologic abnormalities
Flashcard 7: disulfiram
Answer:
Extra: quitting alcohol use inhibits acetylaldehyde dehydrogenase wicked hangover-like symptoms (which are actually the desired effect)
Flashcard 8: Which vitamins, water or fat soluble, are more likely to cause toxicity? Why?
Answer: fat soluble; sequester in fat, less easy to wash out
Flashcard 9: Phase IV
Answer: Patients using the drug in the general population (required post-marketing surveillance)
Extra: Rare or long-term effects
Keywords: P-glycoprotein interactions flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
