Drug-food interactions US Medical PG Flashcards - Medical Study Cards
Master Drug-food interactions with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Drug-food interactions Flashcard Deck - 10 Cards
Flashcard 1: Chronic alcohol use leads to _____ of CYP-450
Answer: induction
Flashcard 2: Monoamine oxidase inhibitors can prevent the metabolism of tyramine (e.g. from wine or cheese ingestion), causing a _____ crisis
Answer: hypertensive
Flashcard 3: What type of drug interaction is an acute decrease in response to a drug after initial/repeated administration?_____
Answer: Tachyphylactic (e.g. nitrates, niacin, phenylephrine, LSD, MDMA)
Flashcard 4: Valproate is an _____ of CYP-450
Answer: inhibitor
Flashcard 5: Acute alcohol use leads to _____ of CYP-450
Answer: inhibition
Flashcard 6: thalidomide
Answer: limb defects (flipper limbs)
Flashcard 7: warfarin
Answer: bone deformities, fetal hemmorhage, abortion, ophthalmologic abnormalities
Flashcard 8: disulfiram
Answer:
Extra: quitting alcohol useinhibits acetylaldehyde dehydrogenasewicked hangover-like symptoms (which are actually the desired effect)
Flashcard 9: Which vitamins, water or fat soluble, are more likely to cause toxicity? Why?
Answer: fat soluble; sequester in fat, less easy to wash out
Flashcard 10: Phase IV
Answer: Patients using the drug in the general population (required post-marketing surveillance)
Extra: Rare or long-term effects
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