GABA-enhancing antiepileptics — Flashcards

Barbiturates exert their effects via binding to an allosteric site on the _____ receptor

The nonbenzodiazepine hypnotics bind to the same GABAA receptor allosteric site as _____

Benzodiazepines _____ the action of GABAA (enhance or inhibit)

Vigabatrin is an anti-epileptic that exerts its effects via inhibition of the enzyme _____

Valproic acid _____ levels of GABA in the CNS via inhibition of GABA transaminase

What is the first line treatment for partial (focal) seizures? _____

What type(s) of seizures (partial, tonic-clonic, or absence) may be treated with vigabatrin and tiagabine? _____

carbamazepine

phenytoin

valproate