Antiepileptic drug interactions US Medical PG Flashcards - Medical Study Cards
Master Antiepileptic drug interactions with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antiepileptic drug interactions Flashcard Deck - 10 Cards
Flashcard 1: What is the most serious adverse effect associated with lamotrigine use?_____
Answer: Steven-Johnson syndrome
Flashcard 2: Which anti-epileptic is most associated with drug-induced lupus? _____
Answer: Phenytoin
Flashcard 3: Stevens-Johnson syndrome typically arises as an adverse _____ reaction
Answer: drug
Flashcard 4: NNRTIs have varying effects on _____ and thus may have many drug interactions
Answer: CYP450
Flashcard 5: What teratogenic effect is associated with valproic acid? _____
Answer: Neural tube defects (e.g. spina bifida)
Flashcard 6: Carbamazepine is an _____ of CYP-450
Answer: inducer
Flashcard 7: Isoniazid _____ cytochrome p450 (induces or inhibits)
Answer: inhibits
Flashcard 8: carbamazepine
Answer: neural tube defects, craniofacial defects, fingernail hypoplasia, developmental delay, IUGR
Flashcard 9: phenytoin
Answer: fetal hydantoin syndrome
Flashcard 10: valproate
Answer: neural tube defects (inhibition of maternal folate absorption)
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