Pulmonary hypertension therapies US Medical PG Flashcards - Medical Study Cards
Master Pulmonary hypertension therapies with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Pulmonary hypertension therapies Flashcard Deck - 10 Cards
Flashcard 1: PDE-5 inhibitors result in increased blood flow in the _____ of the penis
Answer: corpus cavernosum
Flashcard 2: Prostacyclin (PGI2) is synthesized by COX-_____
Answer: 2
Flashcard 3: Prostacyclin (PGI2) is a potent vaso-_____
Answer: dilator
Flashcard 4: PDE-5 inhibitors may cause life-threatening _____ in patients taking nitrates
Answer: hypotension
Flashcard 5: drugs-receptor antagonists may cause _____ (BP) as an adverse effect
Answer: orthostatic hypotension
Flashcard 6: Which prostaglandins mediate vasodilation and increased vascular permeability? _____
Answer: PGE2, PGD2, and PGI2 (prostacyclin)
Flashcard 7: What drug class do vardenafil, tadalafil, and sildenafil belong to?_____
Answer: PDE-5 inhibitors
Flashcard 8: Bosentan antagonizes endothelin-1 receptors, causing _____ pulmonary vascular resistance
Answer: decreased
Flashcard 9: vardenafil
Answer: PDE5 inhibitor
Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia
Flashcard 10: sildenafil
Answer: PDE5 inhibitor
Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia
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