Peripheral vascular disease therapies — Flashcards

Flashcard 1: Dyslipidemia drugs _____ are the only lipid-lowering drugs consistently proven to reduce risk of atherosclerotic heart disease

Answer: Statins

Flashcard 2: Do ADP receptor inhibitors reduce symptoms of claudication in peripheral artery disease? _____

Answer: No

Flashcard 3: Treatment of acute coronary syndromes often includes an _____ receptor inhibitor such as clopidogrel

Answer: ADP

Flashcard 4: What drug class does cilostazol belong to?_____

Answer: antiplatelet PDE-3 inhibitor

Flashcard 5: In addition to preventing platelet aggregation, cilostazol and dipyridamole also cause vaso-_____

Answer: dilation

Flashcard 6: vardenafil

Answer: PDE5 inhibitor

Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia

Flashcard 7: sildenafil

Answer: PDE5 inhibitor

Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia

Flashcard 8: aspirin

Answer:

Extra: increases permeability of the mitochondrial membrane (incomplete)inhibit oxidative phosphorylation

Flashcard 9: ouabain

Answer:

Extra: inhibits Na+-K+ ATPase by binding to K+ site

Flashcard 10: Ischemic priapism is treated with corporal aspiration, intracavernosal _____, or surgical decompression to prevent ischemia

Answer: phenylephrine

Extra:  https://onlinemeded.org?ref=anki