Class III antiarrhythmics (potassium channel blockers) US Medical PG Flashcards - Medical Study Cards
Master Class III antiarrhythmics (potassium channel blockers) with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Class III antiarrhythmics (potassium channel blockers) Flashcard Deck - 10 Cards
Flashcard 1: Cardiovascular (Antiarrhythmics) _____, a class III antiarrhythmic, has many neurologic side effects (e.g. tremor, ataxia, peripheral neuropathy, sleep disturbances)
Answer: Amiodarone
Flashcard 2: What adverse effect is common to sotalol, dofetilide, and ibutilide (class III antiarrhythmics)? _____
Answer: Torsades de pointes
Flashcard 3: What effect do class III antiarrhythmics have on effective refractory period?_____
Answer: Increased ERP
Flashcard 4: _____ is a class III anti-arrhythmic that can produce hyper or hypothyroidism.
Answer: Amiodarone
Flashcard 5: What effect do class III antiarrhythmics have on action potential duration?_____
Answer: Increased AP duration
Flashcard 6: Amiodarone, a class III antiarrhythmic, can induce heart _____, especially with rapid IV administration
Answer: failure
Flashcard 7: vardenafil
Answer: PDE5 inhibitor
Extra: erectile dysfunction patients taking nitrates (lethal hypotension) inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosum headache, flushing, impaired blue-green color vision, hypotension, dyspepsia
Flashcard 8: sildenafil
Answer: PDE5 inhibitor
Extra: erectile dysfunction patients taking nitrates (lethal hypotension) inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosum headache, flushing, impaired blue-green color vision, hypotension, dyspepsia
Flashcard 9: aspirin
Answer:
Extra: increases permeability of the mitochondrial membrane (incomplete) inhibit oxidative phosphorylation
Flashcard 10: ouabain
Answer:
Extra: inhibits Na+-K+ ATPase by binding to K+ site
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